BM2KL_HUMAN
ID BM2KL_HUMAN Reviewed; 411 AA.
AC Q5H9B9;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 2.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Putative BMP-2-inducible kinase-like protein;
GN Name=BMP2KL;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; Z83843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q5H9B9; -.
DR iPTMnet; Q5H9B9; -.
DR PhosphoSitePlus; Q5H9B9; -.
DR BioMuta; HGNC:17080; -.
DR DMDM; 187470879; -.
DR EPD; Q5H9B9; -.
DR MassIVE; Q5H9B9; -.
DR PeptideAtlas; Q5H9B9; -.
DR PRIDE; Q5H9B9; -.
DR ProteomicsDB; 62879; -.
DR GeneCards; BMP2KL; -.
DR HGNC; HGNC:17080; BMP2KL.
DR neXtProt; NX_Q5H9B9; -.
DR InParanoid; Q5H9B9; -.
DR PhylomeDB; Q5H9B9; -.
DR Pharos; Q5H9B9; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q5H9B9; protein.
DR InterPro; IPR026105; BMP-2-ind_kinase.
DR InterPro; IPR028182; BMP2K_C.
DR PANTHER; PTHR22967:SF10; PTHR22967:SF10; 1.
DR Pfam; PF15282; BMP2K_C; 1.
PE 5: Uncertain;
KW Coiled coil; Reference proteome.
FT CHAIN 1..411
FT /note="Putative BMP-2-inducible kinase-like protein"
FT /id="PRO_0000331579"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 47..71
FT /evidence="ECO:0000255"
FT COMPBIAS 231..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 46091 MW; 39B8C370C465D39B CRC64;
MIAPSPKSSE EEGQKDEEVL QGEQGDFNDN DTEPENLGHR PLLMDSEDEE EEEKRSSDSD
YEQAKAKYSD MSPVYRDKSG SGPTQDINTI LLTSAQLSSD VGVETPKQEF DIFGAVPFFA
VCAQQPQQEK NEKSLPQHRF PATGLQQEEF DVFTKAPFSK KVNVQECHAV GPETHPKSID
IFDFTPFQPF LTSTSKSESN EDLFGLVPFE EIMGSQQQKV KQRSLQKLSS RQRRTKQDMS
KSNGKRHHGT PTSKKKTLKP TYRTPERARR HKKVGRRVSQ TSNEFVTISD SKENIGAAVT
DGNDRGNVLQ LEESLLDPFG AKPFHPPDLS WHPLHQGLND IRADHNTVLP KQPRQNSLHG
SFHSADVLTM DDFGAMPFTE LVVQSITLQQ SQQSQPVELD PFGAAPFPSK Q