SYN1L_BOVIN
ID SYN1L_BOVIN Reviewed; 238 AA.
AC A4IFJ1;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=Synapse differentiation-inducing gene protein 1-like;
DE AltName: Full=Capucin;
DE AltName: Full=Dispanin subfamily C member 1;
DE Short=DSPC1;
DE AltName: Full=Transmembrane protein 90A;
GN Name=SYNDIG1L; Synonyms=TMEM90A;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Basal ganglia;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENE FAMILY.
RX PubMed=22363774; DOI=10.1371/journal.pone.0031961;
RA Sallman Almen M., Bringeland N., Fredriksson R., Schioth H.B.;
RT "The dispanins: a novel gene family of ancient origin that contains 14
RT human members.";
RL PLoS ONE 7:E31961-E31961(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Golgi apparatus, cis-Golgi network
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CD225/Dispanin family. {ECO:0000305}.
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DR EMBL; BC134605; AAI34606.1; -; mRNA.
DR RefSeq; NP_001077248.1; NM_001083779.1.
DR AlphaFoldDB; A4IFJ1; -.
DR STRING; 9913.ENSBTAP00000005527; -.
DR PaxDb; A4IFJ1; -.
DR GeneID; 617660; -.
DR KEGG; bta:617660; -.
DR CTD; 646658; -.
DR eggNOG; ENOG502QPQE; Eukaryota.
DR InParanoid; A4IFJ1; -.
DR OrthoDB; 1273993at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR InterPro; IPR007593; CD225/Dispanin_fam.
DR Pfam; PF04505; CD225; 1.
PE 2: Evidence at transcript level;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..238
FT /note="Synapse differentiation-inducing gene protein 1-
FT like"
FT /id="PRO_0000332724"
FT TOPO_DOM 1..162
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 184..205
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 227..238
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..146
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 238 AA; 25822 MW; 04A650D22E902B08 CRC64;
MESLSELQNP LLPRSPTHLH GPYPYPEASP AWPCREKIYS YLLGGAGPAH AHQLLDPGSL
QLAVEAWYRP SCLLGRDKVK EPRPGSCETS FTEGREPPAG PTERSTEPGQ AEEDVAIQTV
SYGVQEEFQG QEGDPEEEES DATSTESESE DNFLTLPPRD HLGLTIFSML CCFWPLGIAA
FYFSQGTSKA ISKGDFRLAN TTSRRALFLA TLSIAVGAGL YVAVVVALAA YMSQNGHS