ABR1_ARATH
ID ABR1_ARATH Reviewed; 391 AA.
AC Q9FGF8;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Ethylene-responsive transcription factor ABR1;
DE AltName: Full=Protein ABA REPRESSOR 1;
GN Name=ABR1; Synonyms=ERF111; OrderedLocusNames=At5g64750; ORFNames=MVP7.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, INDUCTION, AND TISSUE SPECIFICITY.
RX PubMed=16227468; DOI=10.1104/pp.105.066324;
RA Pandey G.K., Grant J.J., Cheong Y.H., Kim B.G., Li L., Luan S.;
RT "ABR1, an APETALA2-domain transcription factor that functions as a
RT repressor of ABA response in Arabidopsis.";
RL Plant Physiol. 139:1185-1193(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
RN [6]
RP INDUCTION BY ABSCISIC ACID; SALT AND YY1.
RC STRAIN=cv. Columbia;
RX PubMed=26961720; DOI=10.1016/j.molp.2016.02.010;
RA Li T., Wu X.-Y., Li H., Song J.-H., Liu J.-Y.;
RT "A dual-function transcription factor, AtYY1, is a novel negative regulator
RT of the Arabidopsis ABA response network.";
RL Mol. Plant 9:650-661(2016).
CC -!- FUNCTION: Negative regulator of the abscisic acid (ABA) signaling
CC pathway involved in seed germination and in responses to stress
CC conditions. Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). {ECO:0000250,
CC ECO:0000269|PubMed:16227468}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Ubiquitous with lower levels in seeds and siliques.
CC {ECO:0000269|PubMed:16227468}.
CC -!- INDUCTION: By abscisic acid (ABA) and stresses, including cold, drought
CC and salt (PubMed:16227468, PubMed:26961720). Triggered by YY1
CC (PubMed:26961720). {ECO:0000269|PubMed:16227468,
CC ECO:0000269|PubMed:26961720}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AB025637; BAB10308.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97946.1; -; Genomic_DNA.
DR EMBL; AY140092; AAM98233.1; -; mRNA.
DR EMBL; BT008480; AAP37839.1; -; mRNA.
DR RefSeq; NP_201280.1; NM_125871.5.
DR AlphaFoldDB; Q9FGF8; -.
DR SMR; Q9FGF8; -.
DR BioGRID; 21838; 28.
DR IntAct; Q9FGF8; 27.
DR STRING; 3702.AT5G64750.1; -.
DR PaxDb; Q9FGF8; -.
DR PRIDE; Q9FGF8; -.
DR ProteomicsDB; 244629; -.
DR EnsemblPlants; AT5G64750.1; AT5G64750.1; AT5G64750.
DR GeneID; 836596; -.
DR Gramene; AT5G64750.1; AT5G64750.1; AT5G64750.
DR KEGG; ath:AT5G64750; -.
DR Araport; AT5G64750; -.
DR TAIR; locus:2176095; AT5G64750.
DR eggNOG; ENOG502S34Q; Eukaryota.
DR HOGENOM; CLU_042594_2_5_1; -.
DR InParanoid; Q9FGF8; -.
DR OMA; EMGNAVY; -.
DR OrthoDB; 1085802at2759; -.
DR PhylomeDB; Q9FGF8; -.
DR PRO; PR:Q9FGF8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGF8; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEP:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0009788; P:negative regulation of abscisic acid-activated signaling pathway; IMP:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:UniProtKB.
DR GO; GO:0009749; P:response to glucose; IEP:TAIR.
DR GO; GO:0006970; P:response to osmotic stress; IEP:TAIR.
DR GO; GO:1902074; P:response to salt; IEP:UniProtKB.
DR GO; GO:0062211; P:root regeneration; IMP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR044808; ERF_plant.
DR PANTHER; PTHR31190; PTHR31190; 1.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Abscisic acid signaling pathway; Activator; DNA-binding;
KW Ethylene signaling pathway; Nucleus; Reference proteome; Stress response;
KW Transcription; Transcription regulation.
FT CHAIN 1..391
FT /note="Ethylene-responsive transcription factor ABR1"
FT /id="PRO_0000297915"
FT DNA_BIND 184..241
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 45..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 42814 MW; 0755E9BE5F2046FB CRC64;
MCVLKVANQE DNVGKKAESI RDDDHRTLSE IDQWLYLFAA EDDHHRHSFP TQQPPPSSSS
SSLISGFSRE MEMSAIVSAL THVVAGNVPQ HQQGGGEGSG EGTSNSSSSS GQKRRREVEE
GGAKAVKAAN TLTVDQYFSG GSSTSKVREA SSNMSGPGPT YEYTTTATAS SETSSFSGDQ
PRRRYRGVRQ RPWGKWAAEI RDPFKAARVW LGTFDNAESA ARAYDEAALR FRGNKAKLNF
PENVKLVRPA STEAQPVHQT AAQRPTQSRN SGSTTTLLPI RPASNQSVHS QPLMQSYNLS
YSEMARQQQQ FQQHHQQSLD LYDQMSFPLR FGHTGGSMMQ STSSSSSHSR PLFSPAAVQP
PPESASETGY LQDIQWPSDK TSNNYNNSPS S
