ID   BMPA2_BORGP             Reviewed;         337 AA.
AC   O31357; O31360; Q661N5;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 2.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Basic membrane protein A2;
DE   AltName: Full=Immunodominant antigen P39;
DE   Flags: Precursor;
GN   Name=bmpA2; Synonyms=bmpA, bmpA-2; OrderedLocusNames=BG0384;
OS   Borrelia garinii subsp. bavariensis (strain ATCC BAA-2496 / DSM 23469 /
OS   PBi) (Borrelia bavariensis).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=290434;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2496 / DSM 23469 / PBi;
RX   PubMed=15547252; DOI=10.1093/nar/gkh953;
RA   Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U.,
RA   Schilhabel M., Wilske B., Suehnel J., Platzer M.;
RT   "Comparative analysis of the Borrelia garinii genome.";
RL   Nucleic Acids Res. 32:6038-6046(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 15-337.
RC   STRAIN=ATCC BAA-2496 / DSM 23469 / PBi, and PLi;
RX   PubMed=9350727; DOI=10.1128/jcm.35.11.2752-2758.1997;
RA   Roessler D., Hauser U., Wilske B.;
RT   "Heterogeneity of BmpA (P39) among European isolates of Borrelia
RT   burgdorferi sensu lato and influence of interspecies variability on
RT   serodiagnosis.";
RL   J. Clin. Microbiol. 35:2752-2758(1997).
CC   -!- FUNCTION: Not known; immunogenic protein.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BMP lipoprotein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000013; AAU07236.1; -; Genomic_DNA.
DR   EMBL; X97244; CAA65883.1; -; Genomic_DNA.
DR   EMBL; X97238; CAA65877.1; -; Genomic_DNA.
DR   RefSeq; WP_011193710.1; NZ_CP028872.1.
DR   AlphaFoldDB; O31357; -.
DR   SMR; O31357; -.
DR   STRING; 290434.BG0384; -.
DR   EnsemblBacteria; AAU07236; AAU07236; BG0384.
DR   KEGG; bga:BG0384; -.
DR   eggNOG; COG1744; Bacteria.
DR   HOGENOM; CLU_038813_0_2_12; -.
DR   OMA; DYYANDW; -.
DR   OrthoDB; 603910at2; -.
DR   Proteomes; UP000002276; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR003760; PnrA-like.
DR   Pfam; PF02608; Bmp; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000305"
FT   CHAIN           18..337
FT                   /note="Basic membrane protein A2"
FT                   /id="PRO_0000017999"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
FT   VARIANT         22
FT                   /note="G -> D (in strain: PLi)"
FT   VARIANT         26
FT                   /note="S -> N (in strain: PLi)"
FT   VARIANT         107
FT                   /note="P -> S (in strain: PLi)"
FT   VARIANT         125
FT                   /note="T -> A (in strain: PLi)"
FT   VARIANT         194
FT                   /note="N -> D (in strain: PLi)"
FT   VARIANT         219
FT                   /note="S -> G (in strain: PLi)"
FT   VARIANT         253
FT                   /note="I -> V (in strain: PLi)"
FT   VARIANT         257
FT                   /note="A -> S (in strain: PLi)"
FT   VARIANT         264
FT                   /note="S -> A (in strain: PLi)"
FT   VARIANT         271
FT                   /note="N -> S (in strain: PLi)"
FT   CONFLICT        337
FT                   /note="E -> EFI (in Ref. 2; CAA65883/CAA65877)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   337 AA;  36878 MW;  0D35479954FAFB3A CRC64;
     MNKLLLLILF ECIIFLSCSG KGSLESGIPK VSVIVNGTFD DKSFNESALN GIKKVKEEFK
     IELVLKESST NSYLSDLEGL KDAGSNLIWL IGYRFSDVAK AVSLQNPEIK YAIIDPVYSE
     EPIPTNLVGM TFRAQEGAFL TGYIAAKVSK TGKIGFLGGI EGEIVDAFRY GYEAGAKYAN
     KDIKISAHYI GSFNDVEAGR SVATKMYSDG IDIIHHAASL GGIGAIEVAK ELGSGHYIIG
     VDEDQSYLAP NNIITSATKD VGRSLNIFTS NYLKTNTFEG GRLINYGLKE GVVGFVKNPK
     MIPFELEKEI DNLSSKIINQ EIIVPYNKES YEKFLKE