BMPA_BORAF
ID BMPA_BORAF Reviewed; 325 AA.
AC P0C223; O31280; O31281; O31282; O31283;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 28-NOV-2006, sequence version 1.
DT 25-MAY-2022, entry version 39.
DE RecName: Full=Basic membrane protein A;
DE AltName: Full=Immunodominant antigen P39;
DE Flags: Precursor; Fragment;
GN Name=bmpA;
OS Borreliella afzelii (Borrelia afzelii).
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX NCBI_TaxID=29518;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PLe, PLj7, and PWudI;
RX PubMed=9350727; DOI=10.1128/jcm.35.11.2752-2758.1997;
RA Roessler D., Hauser U., Wilske B.;
RT "Heterogeneity of BmpA (P39) among European isolates of Borrelia
RT burgdorferi sensu lato and influence of interspecies variability on
RT serodiagnosis.";
RL J. Clin. Microbiol. 35:2752-2758(1997).
CC -!- FUNCTION: Not known; immunogenic protein.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BMP lipoprotein family. {ECO:0000305}.
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DR EMBL; X97237; CAA65876.1; -; Genomic_DNA.
DR EMBL; X97239; CAA65878.1; -; Genomic_DNA.
DR EMBL; X97241; CAA65880.1; -; Genomic_DNA.
DR AlphaFoldDB; P0C223; -.
DR SMR; P0C223; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR003760; PnrA-like.
DR Pfam; PF02608; Bmp; 1.
DR SUPFAM; SSF53822; SSF53822; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL <1..3
FT /evidence="ECO:0000305"
FT CHAIN 4..325
FT /note="Basic membrane protein A"
FT /id="PRO_0000017997"
FT LIPID 4
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 4
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
FT VARIANT 111
FT /note="A -> S (in strain: PLe)"
FT VARIANT 200
FT /note="I -> T (in strain: PLj7)"
FT VARIANT 240
FT /note="I -> V (in strain: PLj7)"
FT VARIANT 254
FT /note="L -> F (in strain: PLe)"
FT NON_TER 1
SQ SEQUENCE 325 AA; 35368 MW; B00BAF8727186B6F CRC64;
FLSCSGKSGL ESGIPKVSLV IDGTFDDKSF NESALNGVKK LKEEFEIELV LKESSTNSYL
SDLEGLKDAG SNLIWLIGYK FSDVAKAVSL QNSEMKYAII DPVYSNEPIP ANLVGMTFRA
QEGAFLTGYI AAKVSKTGKI GFLGGIEGDI VDAFRYGYEA GAKYANKDIK IFSQYIGSFS
DLEAGRSVAT KMYSDGIDII HHAAGLGGIG AIEVAKELGS GHYIIGVDED QSYLAPNNVI
TSTTKDVGRS LNLLTSNYLK TNTFEGGKLI NYGLKEGVVG FVRNPKMIPF EVEKEIDSLS
SKIINKEVIV PYNKESYEKF LKEFI