ID   SYRM2_SINFN             Reviewed;         339 AA.
AC   P55733;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=HTH-type transcriptional regulator SyrM 2;
DE   AltName: Full=Symbiotic regulator homolog 2;
GN   Name=syrM2; OrderedLocusNames=NGR_a00470; ORFNames=y4zF;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- FUNCTION: Acts in trans to stimulate nod gene expression.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00090; AAB91963.1; -; Genomic_DNA.
DR   RefSeq; NP_444176.1; NC_000914.2.
DR   RefSeq; WP_010875089.1; NC_000914.2.
DR   AlphaFoldDB; P55733; -.
DR   SMR; P55733; -.
DR   PRIDE; P55733; -.
DR   EnsemblBacteria; AAB91963; AAB91963; NGR_a00470.
DR   KEGG; rhi:NGR_a00470; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_39_0_5; -.
DR   OMA; VLQQTDM; -.
DR   OrthoDB; 1591366at2; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Plasmid; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..339
FT                   /note="HTH-type transcriptional regulator SyrM 2"
FT                   /id="PRO_0000105755"
FT   DOMAIN          32..89
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        49..68
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   339 AA;  37536 MW;  CA9C1F1F6B1F25D5 CRC64;
     MDQPAWKNPR TALIVDGSDA ARQRRIPNLA SVDLNLLVEL EALLQYRNIT HAAQHVGRSQ
     PAMSRALSRL RDMFNDDLLV RGSSGLVPTP QAEHLAQMLP SVLNAIRELV SCSSGLRDLR
     SKVTMAMPDH QSLVLLPYLL PRLGERVPHV DIVTEPLLDG ALRRLEQGEI DFAIGQIGAA
     PPGYLRRGLY ADRFTCLLRH DHPALEQEWS VGTFAALRHA SIASDSNEGL GQVYDGLVRF
     GLPGPIVVSN VLTAAVVVAM TDLVLMIPNR VATRVATMLP LAIVDPPVEL KPYEVALIWH
     QRCHHDLEHR VLRREIAAAA RMGRLDVSQD QRARRQNDS