BMTI3_RHIMP
ID BMTI3_RHIMP Reviewed; 27 AA.
AC P83604;
DT 27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Kunitz-type serine protease inhibitor 3;
DE Short=BmTI-3;
DE Flags: Fragment;
OS Rhipicephalus microplus (Cattle tick) (Boophilus microplus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae;
OC Rhipicephalus; Boophilus.
OX NCBI_TaxID=6941;
RN [1]
RP PROTEIN SEQUENCE, AND FUNCTION.
RC TISSUE=Larva;
RX PubMed=15556274; DOI=10.1016/j.biochi.2004.09.010;
RA Sasaki S.D., Azzolini S.S., Hirata I.Y., Andreotti R., Tanaka A.S.;
RT "Boophilus microplus tick larvae, a rich source of Kunitz type serine
RT proteinase inhibitors.";
RL Biochimie 86:643-649(2004).
CC -!- FUNCTION: Inhibits bovine trypsin and human neutrophil elastase.
CC {ECO:0000269|PubMed:15556274}.
CC -!- SUBCELLULAR LOCATION: Secreted.
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DR AlphaFoldDB; P83604; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Protease inhibitor; Secreted;
KW Serine protease inhibitor.
FT CHAIN 1..>27
FT /note="Kunitz-type serine protease inhibitor 3"
FT /id="PRO_0000155452"
FT DOMAIN 1..>27
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00031"
FT NON_TER 27
SQ SEQUENCE 27 AA; 3193 MW; D55586CDC75E201F CRC64;
EVHNFACLGK PDPGGCAHYI YRRYYYV