SYR_CHLPD
ID SYR_CHLPD Reviewed; 551 AA.
AC A1BJV9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Arginine--tRNA ligase {ECO:0000255|HAMAP-Rule:MF_00123};
DE EC=6.1.1.19 {ECO:0000255|HAMAP-Rule:MF_00123};
DE AltName: Full=Arginyl-tRNA synthetase {ECO:0000255|HAMAP-Rule:MF_00123};
DE Short=ArgRS {ECO:0000255|HAMAP-Rule:MF_00123};
GN Name=argS {ECO:0000255|HAMAP-Rule:MF_00123};
GN OrderedLocusNames=Cpha266_2702;
OS Chlorobium phaeobacteroides (strain DSM 266).
OC Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC Chlorobium/Pelodictyon group; Chlorobium.
OX NCBI_TaxID=290317;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 266;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.,
RA Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T.,
RA Overmann J., Bryant D.A., Richardson P.;
RT "Complete sequence of Chlorobium phaeobacteroides DSM 266.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-
CC tRNA(Arg); Xref=Rhea:RHEA:20301, Rhea:RHEA-COMP:9658, Rhea:RHEA-
CC COMP:9673, ChEBI:CHEBI:30616, ChEBI:CHEBI:32682, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:78513, ChEBI:CHEBI:456215;
CC EC=6.1.1.19; Evidence={ECO:0000255|HAMAP-Rule:MF_00123};
CC -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00123}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00123}.
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000255|HAMAP-Rule:MF_00123}.
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DR EMBL; CP000492; ABL66686.1; -; Genomic_DNA.
DR RefSeq; WP_015961213.1; NC_008639.1.
DR AlphaFoldDB; A1BJV9; -.
DR SMR; A1BJV9; -.
DR STRING; 290317.Cpha266_2702; -.
DR EnsemblBacteria; ABL66686; ABL66686; Cpha266_2702.
DR KEGG; cph:Cpha266_2702; -.
DR eggNOG; COG0018; Bacteria.
DR HOGENOM; CLU_006406_0_1_10; -.
DR OMA; NKPLHLG; -.
DR OrthoDB; 1146366at2; -.
DR Proteomes; UP000008701; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR CDD; cd00671; ArgRS_core; 1.
DR Gene3D; 3.30.1360.70; -; 1.
DR Gene3D; 3.40.50.620; -; 1.
DR HAMAP; MF_00123; Arg_tRNA_synth; 1.
DR InterPro; IPR001278; Arg-tRNA-ligase.
DR InterPro; IPR005148; Arg-tRNA-synth_N.
DR InterPro; IPR036695; Arg-tRNA-synth_N_sf.
DR InterPro; IPR035684; ArgRS_core.
DR InterPro; IPR008909; DALR_anticod-bd.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR PANTHER; PTHR11956; PTHR11956; 1.
DR Pfam; PF03485; Arg_tRNA_synt_N; 1.
DR Pfam; PF05746; DALR_1; 1.
DR Pfam; PF00750; tRNA-synt_1d; 1.
DR PRINTS; PR01038; TRNASYNTHARG.
DR SMART; SM01016; Arg_tRNA_synt_N; 1.
DR SMART; SM00836; DALR_1; 1.
DR SUPFAM; SSF47323; SSF47323; 1.
DR SUPFAM; SSF55190; SSF55190; 1.
DR TIGRFAMs; TIGR00456; argS; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT CHAIN 1..551
FT /note="Arginine--tRNA ligase"
FT /id="PRO_1000018012"
FT MOTIF 123..133
FT /note="'HIGH' region"
SQ SEQUENCE 551 AA; 61751 MW; E072657A4C0039CC CRC64;
MHDFFLPVIK NALLSLAVSS DKPVLIERPA DKKFGDFSTN IAFLIAKESR RNPKEFAGEL
IAHLSFPPDT IKSMTVAGPG FINFFLTPTF IMQSVEQILL EGKGYGRSCL GKGKKAIVEY
VSANPTGPLT IGRGRGGVLG DCIANLLETQ SYAVTREYYF NDAGRQMQIL GESVRFRYLE
LCGVAETFPE THYQGAYIRE IAESLFAGHG AALQGVHDLL PFIKSAETII FKSIKNTLER
IGIRHDSFFN EHTLYHREGS GQSANEEVID LLREKQFIGE YDGATWFLTS RIGQEKDKVL
IKSSGEPSYR LPDIAYHITK FKRGYDLMVN VFGADHIDEY PDVLEALKIL GYDASRIQVA
INQFVTTTVD GQSVKMSTRK GNADLLDDLV DDVGPDATRL FFIMRSKDSH LNFDIDLAKK
QSKDNPVFYL HYAHARICSL LRMAALENGF DPDGSGHHLL QLLDSEPELR LGLLLLEYPQ
MITASIRLLE PQKMVDYLHS VAELYHKFYQ ECPILKAEPD ISKARLFLSL ATKQVLCNGF
RILGISAPES M