ID   BNCA_BENHI              Reviewed;          27 AA.
AC   P83960;
DT   05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2004, sequence version 1.
DT   25-MAY-2022, entry version 29.
DE   RecName: Full=Alpha-benincasin;
DE   Flags: Fragment;
OS   Benincasa hispida (Wax gourd) (Cucurbita hispida).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Benincasa.
OX   NCBI_TaxID=102211;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   STRAIN=Dong-gua {ECO:0000269|PubMed:12576080};
RC   TISSUE=Seed {ECO:0000269|PubMed:12576080};
RX   PubMed=12576080; DOI=10.1016/s0196-9781(02)00271-1;
RA   Ng T.B., Parkash A., Tso W.W.;
RT   "Purification and characterization of alpha- and beta-benincasins,
RT   arginine/glutamate-rich peptides with translation-inhibiting activity from
RT   wax gourd seeds.";
RL   Peptides 24:11-16(2003).
CC   -!- FUNCTION: Has weak antifungal activity toward C.comatus and P.piricola
CC       but not toward M.arachidicola. Inhibits cell-free translation in rabbit
CC       reticulocyte lysate system. {ECO:0000269|PubMed:12576080}.
CC   -!- MISCELLANEOUS: IC(50) of 20 pM in rabbit reticulocyte.
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DR   AlphaFoldDB; P83960; -.
DR   PRIDE; P83960; -.
DR   GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Fungicide.
FT   PEPTIDE         1..>27
FT                   /note="Alpha-benincasin"
FT                   /id="PRO_0000045091"
FT   NON_TER         27
FT                   /evidence="ECO:0000303|PubMed:12576080"
SQ   SEQUENCE   27 AA;  3743 MW;  FEC2041F751F5E24 CRC64;
     RDWERREFER RQNELRREQE QRREELL