ID   SYR_PSYWF               Reviewed;         609 AA.
AC   A5WC58;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Arginine--tRNA ligase {ECO:0000255|HAMAP-Rule:MF_00123};
DE            EC=6.1.1.19 {ECO:0000255|HAMAP-Rule:MF_00123};
DE   AltName: Full=Arginyl-tRNA synthetase {ECO:0000255|HAMAP-Rule:MF_00123};
DE            Short=ArgRS {ECO:0000255|HAMAP-Rule:MF_00123};
GN   Name=argS {ECO:0000255|HAMAP-Rule:MF_00123};
GN   OrderedLocusNames=PsycPRwf_0294;
OS   Psychrobacter sp. (strain PRwf-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Psychrobacter.
OX   NCBI_TaxID=349106;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PRwf-1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Kim E., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome of Psychrobacter sp. PRwf-1.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-
CC         tRNA(Arg); Xref=Rhea:RHEA:20301, Rhea:RHEA-COMP:9658, Rhea:RHEA-
CC         COMP:9673, ChEBI:CHEBI:30616, ChEBI:CHEBI:32682, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78513, ChEBI:CHEBI:456215;
CC         EC=6.1.1.19; Evidence={ECO:0000255|HAMAP-Rule:MF_00123};
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00123}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00123}.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00123}.
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DR   EMBL; CP000713; ABQ93249.1; -; Genomic_DNA.
DR   RefSeq; WP_011959583.1; NC_009524.1.
DR   AlphaFoldDB; A5WC58; -.
DR   SMR; A5WC58; -.
DR   STRING; 349106.PsycPRwf_0294; -.
DR   EnsemblBacteria; ABQ93249; ABQ93249; PsycPRwf_0294.
DR   KEGG; prw:PsycPRwf_0294; -.
DR   eggNOG; COG0018; Bacteria.
DR   HOGENOM; CLU_006406_0_1_6; -.
DR   OMA; NKPLHLG; -.
DR   OrthoDB; 1146366at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   CDD; cd00671; ArgRS_core; 1.
DR   Gene3D; 3.30.1360.70; -; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   HAMAP; MF_00123; Arg_tRNA_synth; 1.
DR   InterPro; IPR001278; Arg-tRNA-ligase.
DR   InterPro; IPR005148; Arg-tRNA-synth_N.
DR   InterPro; IPR036695; Arg-tRNA-synth_N_sf.
DR   InterPro; IPR035684; ArgRS_core.
DR   InterPro; IPR008909; DALR_anticod-bd.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   PANTHER; PTHR11956; PTHR11956; 1.
DR   Pfam; PF03485; Arg_tRNA_synt_N; 1.
DR   Pfam; PF05746; DALR_1; 1.
DR   Pfam; PF00750; tRNA-synt_1d; 1.
DR   PRINTS; PR01038; TRNASYNTHARG.
DR   SMART; SM01016; Arg_tRNA_synt_N; 1.
DR   SMART; SM00836; DALR_1; 1.
DR   SUPFAM; SSF47323; SSF47323; 1.
DR   SUPFAM; SSF55190; SSF55190; 1.
DR   TIGRFAMs; TIGR00456; argS; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis.
FT   CHAIN           1..609
FT                   /note="Arginine--tRNA ligase"
FT                   /id="PRO_1000071396"
FT   MOTIF           132..142
FT                   /note="'HIGH' region"
SQ   SEQUENCE   609 AA;  67335 MW;  72C2545C658B92C3 CRC64;
     MSQAQIDEIF ALLDSAAKVL IDQGVLPADW QNNSQITRSK SPEHGDYASN IALTAAKAAK
     SNPRALAEQL TAALPANDSI AKLEIAGPGF INIFLNTDAK FAVLDAIFAK NQKYGLTDEF
     ANKKIQVEFV SANPTSSLHV GHGRGAAFGM SVANLLEAVG YEVTREYYVN DAGRQMDILA
     TSTYLRYLQL NGEQIHFPVG GYQGDYVTDI AQTIKTQQND AYVHSYADIS ANAPEDEVSE
     VNDAGEKEVV SGDKNAHIDV IIANSKQALG DNYAVFLNAA LSEILGDIKD DLNEFGVRFE
     RWFSEKSIAD EIEPVLAELD SKGHLYEKDG NIWFRSTDFG DEKDRVVRRA NGLTTYFASD
     IAYHKNKFER GFDTVINVWG ADHHGYIARV RAALTALGID EKRLEVILVQ FVALWRGEEK
     IQMSSRSGKF VTLRELREEV GNDAARFYYV ARKPEVHIDF DLELAKSQSK DNAVYYIQYA
     HARVCSVLEK LAAKGFDVDD AQGSAQQHLL TADAESELIK LLAAYPATLK RAATGYDPHV
     LTNYLKDLAS LFHAWYNDNR ILPVSIIADE TPSQEELDMM QARLRLSKAV RQVLANGLSL
     LGLSAPTSM