BNIP5_MOUSE
ID BNIP5_MOUSE Reviewed; 669 AA.
AC Q8CC96; B2KF61; Q148X2;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein BNIP5 {ECO:0000305};
GN Name=Bnip5;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cecum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK033585; BAC28374.1; -; mRNA.
DR EMBL; AC140278; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CT025867; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC117930; AAI17931.1; -; mRNA.
DR CCDS; CCDS28586.1; -.
DR RefSeq; NP_766038.1; NM_172450.3.
DR AlphaFoldDB; Q8CC96; -.
DR STRING; 10090.ENSMUSP00000050646; -.
DR PhosphoSitePlus; Q8CC96; -.
DR PaxDb; Q8CC96; -.
DR PRIDE; Q8CC96; -.
DR Antibodypedia; 49825; 52 antibodies from 10 providers.
DR DNASU; 207819; -.
DR Ensembl; ENSMUST00000062357; ENSMUSP00000050646; ENSMUSG00000048905.
DR GeneID; 207819; -.
DR KEGG; mmu:207819; -.
DR UCSC; uc008bru.1; mouse.
DR CTD; 389384; -.
DR MGI; MGI:1925441; Bnip5.
DR VEuPathDB; HostDB:ENSMUSG00000048905; -.
DR eggNOG; ENOG502T262; Eukaryota.
DR GeneTree; ENSGT00390000001176; -.
DR HOGENOM; CLU_028338_0_0_1; -.
DR InParanoid; Q8CC96; -.
DR OMA; RCPRKPL; -.
DR OrthoDB; 475879at2759; -.
DR PhylomeDB; Q8CC96; -.
DR TreeFam; TF338223; -.
DR BioGRID-ORCS; 207819; 3 hits in 73 CRISPR screens.
DR PRO; PR:Q8CC96; -.
DR Proteomes; UP000000589; Chromosome 17.
DR RNAct; Q8CC96; protein.
DR Bgee; ENSMUSG00000048905; Expressed in jejunum and 105 other tissues.
DR ExpressionAtlas; Q8CC96; baseline and differential.
DR Genevisible; Q8CC96; MM.
DR InterPro; IPR031362; BNIP5.
DR PANTHER; PTHR22435; PTHR22435; 1.
DR Pfam; PF15661; CF222; 1.
PE 2: Evidence at transcript level;
KW Isopeptide bond; Reference proteome; Ubl conjugation.
FT CHAIN 1..669
FT /note="Protein BNIP5"
FT /id="PRO_0000317188"
FT REGION 1..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CROSSLNK 314
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P0C671"
FT CONFLICT 63
FT /note="A -> V (in Ref. 3; AAI17931)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 669 AA; 72970 MW; 1E30636A45FEB39B CRC64;
MPRSRNPSQG MPRDSSDSCG LSPVETPKGK KRARSLDRQV PRKKDPESSN TRCPSSATCR
RTASDGARSS ESPSHFAEAQ GATAAALPPG EGRGFLPSEQ GPPEDTKKER LPREAQQSWL
RLVLNILLMR IEEPREKASR ASKGKGDLPE AAEEPALRKK SHEKRTSRKK HSHRKPIAEE
PPGPQTAEAQ GREDVPPSLA ASSAPHEIAL GLICRGGPDS DLPQALPTEG DHAETPDSFG
QASGPPLEED PRKPDQDDVI WQIVELLKKA GDQLEEEQVQ IPQPEAVPPR KPTPLPRKKS
QEKKSSLKRV LSLKKPASEE PKRVGTATTL GPETRPKRPS FLPLCVSSQR ASTSSSLDLE
APEFQEVPSV DGGGSHPSEL HTPAAIFQGP EEKPLLDRAS ESREFRRKIL VLLQSAEDER
GEQEAQAQEA EKAGENPTPA GKVKSQVKKS NLRRAFSLRK HSSKDSKKTE ASGTPGSGSL
EARPPKKHGF LPMCVSGHRA SISSSPESLE FQKTEAAGGA PAGSPGAPFQ ARSHTPDEGP
SPERAWESKE FMIQKLVASL QEVDRDLGRQ IRKYPSFKRF FNEFSDASLR KLVATLERQK
ASLSEEGRSL ANRPPPCAFG TLNKFAATRS CTICTLMQSR GEYKGHSYAH FLSRKAEQDI
TNLDSQSPD
