ID   SYS1_BOVIN              Reviewed;         156 AA.
AC   Q1RMQ3;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Protein SYS1 homolog;
GN   Name=SYS1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Heart ventricle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein trafficking. May serve as a receptor for
CC       ARFRP1 (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with ARFRP1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SYS1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC114777; AAI14778.1; -; mRNA.
DR   RefSeq; NP_001039992.1; NM_001046527.2.
DR   RefSeq; XP_005214889.1; XM_005214832.2.
DR   AlphaFoldDB; Q1RMQ3; -.
DR   STRING; 9913.ENSBTAP00000006825; -.
DR   PaxDb; Q1RMQ3; -.
DR   Ensembl; ENSBTAT00000006825; ENSBTAP00000006825; ENSBTAG00000005181.
DR   GeneID; 614236; -.
DR   KEGG; bta:614236; -.
DR   CTD; 90196; -.
DR   VEuPathDB; HostDB:ENSBTAG00000005181; -.
DR   VGNC; VGNC:97315; SYS1.
DR   eggNOG; KOG4697; Eukaryota.
DR   GeneTree; ENSGT00940000154347; -.
DR   HOGENOM; CLU_081382_2_1_1; -.
DR   InParanoid; Q1RMQ3; -.
DR   OMA; EYEMVGM; -.
DR   OrthoDB; 1583277at2759; -.
DR   TreeFam; TF105875; -.
DR   Reactome; R-BTA-6811440; Retrograde transport at the Trans-Golgi-Network.
DR   Proteomes; UP000009136; Chromosome 13.
DR   Bgee; ENSBTAG00000005181; Expressed in retina and 106 other tissues.
DR   ExpressionAtlas; Q1RMQ3; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0006895; P:Golgi to endosome transport; IBA:GO_Central.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IBA:GO_Central.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IBA:GO_Central.
DR   InterPro; IPR016973; Integral_membrane_SYS1.
DR   InterPro; IPR019185; Integral_membrane_SYS1-rel.
DR   PANTHER; PTHR12952; PTHR12952; 1.
DR   Pfam; PF09801; SYS1; 1.
DR   PIRSF; PIRSF031402; SYS1_homologue; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..156
FT                   /note="Protein SYS1 homolog"
FT                   /id="PRO_0000329299"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   156 AA;  17445 MW;  E212B699018DCF3E CRC64;
     MAGQFRSYVW DPLLILSQIV LMQTVYYGSL GLWLALVDGL VHSSPSLDQV FDAEILGFST
     PPGRLSTMSF VLNALTCALG LLYFIRRGKQ CLDFTVTVHF FHLLGCWLYS SRFPSALTWW
     LVQAVCIALM AVIGEYLCMR SELKEIPLNS APKSSV