SYS1_PAPAN
ID SYS1_PAPAN Reviewed; 156 AA.
AC A4K2N5;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=Protein SYS1 homolog;
GN Name=SYS1;
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=17267810; DOI=10.1101/gr.6004607;
RG NISC comparative sequencing program;
RA Hurle B., Swanson W., Green E.D.;
RT "Comparative sequence analyses reveal rapid and divergent evolutionary
RT changes of the WFDC locus in the primate lineage.";
RL Genome Res. 17:276-286(2007).
CC -!- FUNCTION: Involved in protein trafficking. May serve as a receptor for
CC ARFRP1 (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with ARFRP1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SYS1 family. {ECO:0000305}.
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DR EMBL; DP000036; ABO52918.1; -; Genomic_DNA.
DR RefSeq; NP_001162205.1; NM_001168734.1.
DR AlphaFoldDB; A4K2N5; -.
DR STRING; 9555.ENSPANP00000017658; -.
DR Ensembl; ENSPANT00000078008; ENSPANP00000058025; ENSPANG00000042818.
DR GeneID; 100137166; -.
DR KEGG; panu:100137166; -.
DR CTD; 90196; -.
DR eggNOG; KOG4697; Eukaryota.
DR GeneTree; ENSGT00940000154347; -.
DR HOGENOM; CLU_081382_2_1_1; -.
DR OMA; EYEMVGM; -.
DR OrthoDB; 1583277at2759; -.
DR Proteomes; UP000028761; Chromosome 16.
DR Bgee; ENSPANG00000024119; Expressed in adult mammalian kidney and 66 other tissues.
DR ExpressionAtlas; A4K2N5; baseline.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR016973; Integral_membrane_SYS1.
DR InterPro; IPR019185; Integral_membrane_SYS1-rel.
DR PANTHER; PTHR12952; PTHR12952; 1.
DR Pfam; PF09801; SYS1; 1.
DR PIRSF; PIRSF031402; SYS1_homologue; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..156
FT /note="Protein SYS1 homolog"
FT /id="PRO_0000329300"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 156 AA; 17615 MW; 541FBB6326C9C0BB CRC64;
MAGQFRSYVW DPLLILSQIV LMQTVYYGSL GLWLALVDGL VRSSPSLDQM FDAEILGFST
PPGRLSMMSF ILNALTCALG LLYFIRRGKQ CLDFTVTVHF FHLLGCWFYS SRFPSALTWW
LVQAVCIALM AVIGEYLCMR TELKEIPLNS APKSNV