SYST_SOLLC
ID SYST_SOLLC Reviewed; 200 AA.
AC P27058;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Systemin;
DE Flags: Precursor;
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC TISSUE=Leaf;
RX PubMed=1549783; DOI=10.1126/science.1549783;
RA McGurl B., Pearce G., Orozco-Cardenas M., Ryan C.A.;
RT "Structure, expression, and antisense inhibition of the systemin precursor
RT gene.";
RL Science 255:1570-1573(1992).
RN [2]
RP PROTEIN SEQUENCE OF 179-196.
RA Pearce G., Strydom D., Johnson S., Ryan C.A.;
RT "A polypeptide from tomato leaves induces wound-inducible proteinase
RT inhibitor proteins.";
RL Science 253:895-898(1991).
RN [3]
RP FUNCTION.
RX PubMed=10708853; DOI=10.1016/s0167-4838(99)00269-1;
RA Ryan C.A.;
RT "The systemin signaling pathway: differential activation of plant defensive
RT genes.";
RL Biochim. Biophys. Acta 1477:112-121(2000).
CC -!- FUNCTION: Activates a lipid-based signal transduction pathway in which
CC linolenic acid is converted to jasmonic acid, a potent activator of
CC defense gene transcription, including proteinase inhibitor.
CC {ECO:0000269|PubMed:10708853}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- TISSUE SPECIFICITY: All organs except the roots. Transported out of
CC wounds to distal tissues.
CC -!- INDUCTION: By wounding; in leaves.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M84800; AAA34182.1; -; Genomic_DNA.
DR EMBL; M84801; AAA34184.1; -; mRNA.
DR PIR; T07149; T07149.
DR RefSeq; NP_001296096.1; NM_001309167.1.
DR AlphaFoldDB; P27058; -.
DR SMR; P27058; -.
DR STRING; 4081.Solyc05g051750.2.1; -.
DR PaxDb; P27058; -.
DR PRIDE; P27058; -.
DR GeneID; 543989; -.
DR KEGG; sly:543989; -.
DR Proteomes; UP000004994; Unplaced.
DR ExpressionAtlas; P27058; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR DisProt; DP01969; -.
DR InterPro; IPR009966; Prosystemin/Systemin.
DR Pfam; PF07376; Prosystemin; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Direct protein sequencing; Hormone; Reference proteome; Repeat.
FT PROPEP 1..178
FT /evidence="ECO:0000269|Ref.2"
FT /id="PRO_0000022461"
FT PEPTIDE 179..196
FT /note="Systemin"
FT /id="PRO_0000022462"
FT PROPEP 197..200
FT /id="PRO_0000022463"
FT REPEAT 3..8
FT /note="1; truncated"
FT REPEAT 37..45
FT /note="2"
FT REPEAT 80..88
FT /note="3"
FT REPEAT 117..125
FT /note="4"
FT REPEAT 145..153
FT /note="5"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 200 AA; 22999 MW; FA251D94BAA9C5A9 CRC64;
MGTPSYDIKN KGDDMQEEPK VKLHHEKGGD EKEKIIEKET PSQDINNKDT ISSYVLRDDT
QEIPKMEHEE GGYVKEKIVE KETISQYIIK IEGDDDAQEK LKVEYEEEEY EKEKIVEKET
PSQDINNKGD DAQEKPKVEH EEGDDKETPS QDIIKMEGEG ALEITKVVCE KIIVREDLAV
QSKPPSKRDP PKMQTDNNKL
