BNS1_YEAST
ID BNS1_YEAST Reviewed; 137 AA.
AC P50084; D6VV10;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Protein BNS1;
GN Name=BNS1; OrderedLocusNames=YGR230W; ORFNames=G8558;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8701610;
RX DOI=10.1002/(sici)1097-0061(19960330)12:4<385::aid-yea910>3.0.co;2-g;
RA van der Aart Q.J.M., Kleine K., Steensma H.Y.;
RT "Sequence analysis of the 43 kb CRM1-YLM9-PET54-DIE2-SMI1-PHO81-YHB4-PFK1
RT region from the right arm of Saccharomyces cerevisiae chromosome VII.";
RL Yeast 12:385-390(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169869;
RA Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL Nature 387:81-84(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP FUNCTION.
RX PubMed=9763445; DOI=10.1091/mbc.9.10.2803;
RA Jaspersen S.L., Charles J.F., Tinker-Kulberg R.L., Morgan D.O.;
RT "A late mitotic regulatory network controlling cyclin destruction in
RT Saccharomyces cerevisiae.";
RL Mol. Biol. Cell 9:2803-2817(1998).
RN [6]
RP FUNCTION.
RX PubMed=10564265; DOI=10.1091/mbc.10.11.3689;
RA Grether M.E., Herskowitz I.;
RT "Genetic and biochemical characterization of the yeast spo12 protein.";
RL Mol. Biol. Cell 10:3689-3703(1999).
RN [7]
RP FUNCTION.
RX PubMed=14551257; DOI=10.1091/mbc.e03-02-0095;
RA Visintin R., Stegmeier F., Amon A.;
RT "The role of the polo kinase Cdc5 in controlling Cdc14 localization.";
RL Mol. Biol. Cell 14:4486-4498(2003).
RN [8]
RP FUNCTION.
RX PubMed=15137939; DOI=10.1016/s0092-8674(04)00413-1;
RA D'Amours D., Stegmeier F., Amon A.;
RT "Cdc14 and condensin control the dissolution of cohesin-independent
RT chromosome linkages at repeated DNA.";
RL Cell 117:455-469(2004).
CC -!- FUNCTION: Component of the FEAR (CDC14 early anaphase release) network
CC which promotes CDC14 release from the nucleolus during early anaphase
CC and is required for the efficient segregation of telomeric and
CC nucleolar regions. Although BNS1 can partially compensate for a lack of
CC SPO12 function when overexpressed, it does not appear to play any role
CC in controlling meiotic nuclear division. {ECO:0000269|PubMed:10564265,
CC ECO:0000269|PubMed:14551257, ECO:0000269|PubMed:15137939,
CC ECO:0000269|PubMed:9763445}.
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DR EMBL; X87941; CAA61180.1; -; Genomic_DNA.
DR EMBL; Z73015; CAA97258.1; -; Genomic_DNA.
DR EMBL; AY558380; AAS56706.1; -; Genomic_DNA.
DR EMBL; BK006941; DAA08321.1; -; Genomic_DNA.
DR PIR; S57695; S57695.
DR RefSeq; NP_011746.3; NM_001181359.3.
DR AlphaFoldDB; P50084; -.
DR SMR; P50084; -.
DR BioGRID; 33482; 45.
DR STRING; 4932.YGR230W; -.
DR PaxDb; P50084; -.
DR PRIDE; P50084; -.
DR EnsemblFungi; YGR230W_mRNA; YGR230W; YGR230W.
DR GeneID; 853145; -.
DR KEGG; sce:YGR230W; -.
DR SGD; S000003462; BNS1.
DR VEuPathDB; FungiDB:YGR230W; -.
DR HOGENOM; CLU_154786_0_0_1; -.
DR InParanoid; P50084; -.
DR OMA; KVAHNTK; -.
DR BioCyc; YEAST:G3O-30908-MON; -.
DR PRO; PR:P50084; -.
DR Proteomes; UP000002311; Chromosome VII.
DR RNAct; P50084; protein.
DR GO; GO:0051321; P:meiotic cell cycle; IGI:SGD.
DR GO; GO:1904750; P:negative regulation of protein localization to nucleolus; IGI:SGD.
DR InterPro; IPR007727; Spo12.
DR Pfam; PF05032; Spo12; 1.
PE 4: Predicted;
KW Cell cycle; Reference proteome.
FT CHAIN 1..137
FT /note="Protein BNS1"
FT /id="PRO_0000202851"
SQ SEQUENCE 137 AA; 15840 MW; E910263C9A0E6320 CRC64;
MSYGGSASQD IVTKLIRKIQ NTSVSCTRRD ENLDSFNQHL KMSLKVAHNT KTFAKHCLHR
QVFKNTYRKR KAVEDQRKNL NTQLRQKFAS PSDNLLSPCS RKLNDHKSKL FSAKSQPKTL
EFVRGKQNIP RKPNVDI
