ID   ABRA_PLAFG              Reviewed;         600 AA.
AC   P23745;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=101 kDa malaria antigen;
DE   AltName: Full=Acidic basic repeat antigen;
DE   AltName: Full=p101;
DE   Flags: Fragment;
GN   Name=ABRA;
OS   Plasmodium falciparum (isolate FCR-3 / Gambia).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5838;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3042768; DOI=10.1016/s0021-9258(18)37973-0;
RA   Weber J.L., Lyon J.A., Wolff R.H., Hall T., Lowell G.H., Chulay J.D.;
RT   "Primary structure of a Plasmodium falciparum malaria antigen located at
RT   the merozoite surface and within the parasitophorous vacuole.";
RL   J. Biol. Chem. 263:11421-11425(1988).
CC   -!- SUBCELLULAR LOCATION: Cell surface {ECO:0000250}. Parasitophorous
CC       vacuole {ECO:0000250}. Note=At the merozoite surface and within the
CC       parasitophorous vacuole. {ECO:0000250}.
CC   -!- PTM: Not glycosylated. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the plasmodium ABRA family. {ECO:0000305}.
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DR   AlphaFoldDB; P23745; -.
DR   BMRB; P23745; -.
DR   SMR; P23745; -.
DR   GO; GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.
DR   GO; GO:0020003; C:symbiont-containing vacuole; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Malaria; Repeat.
FT   CHAIN           <1..>600
FT                   /note="101 kDa malaria antigen"
FT                   /id="PRO_0000217178"
FT   REPEAT          143..148
FT                   /note="1"
FT   REPEAT          149..154
FT                   /note="2"
FT   REPEAT          155..160
FT                   /note="3"
FT   REPEAT          161..166
FT                   /note="4"
FT   REPEAT          167..172
FT                   /note="5"
FT   REPEAT          173..178
FT                   /note="6"
FT   REPEAT          179..184
FT                   /note="7"
FT   REPEAT          185..190
FT                   /note="8"
FT   REGION          119..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..190
FT                   /note="8 X 6 AA tandem repeats of [VT]-N-D-[ED]-[ED]-D"
FT   REGION          376..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          429..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        119..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..190
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        376..390
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        429..445
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         600
SQ   SEQUENCE   600 AA;  69293 MW;  F374614F24AAC938 CRC64;
     QYTDSVTYLM DGFKSANNSA NNGKKNNAEE MKNLVNFLQS HKKLIKALKK NIESIQNKKH
     LIYKNKSYNP LLLSCVKKMN MLKENVDYIQ KNQNLFKELM NQKATYSFVN TKKKIISLKS
     QGHKKETSQN QNENNDNQKY QEVNDEDDVN DEEDTNDDED TNDEEDTNDD EDTNDDEDTN
     DEEDTNDEED HENNNATAYE LGIVPVNDVL NVNMKNMITG NNFMDVVKST LAQSGGLGSN
     DLINFLNQGK EIGENLLNIT KMNLGDKNNL ESFPLDQLNM LKDNLINYEF ILNNLKTSVL
     NKLKDLLLRL LYKAYVSYKK RKAQEKGLPE PTVTNEEYVE ELKKGILDMG IKLLFSKVKS
     LLKKLKNKIF PKKKEDNQAV DTKSMEEPKV KAQPALRGVE PTEDSNIMNS INNVMDEIDF
     FEKELIENNN TPNVVPPTQS KKKNKNETVS GMDENFDNHP ENYFKEEYYY DENDDMEVKV
     KKIGVTLKKF EPLKNGNVSE TIKLIHLGNK DKKHIEAINN DIQIIKQELQ AIYNELMNYT
     NGNKNIQQIF QQNILENDVL NQETEEEMEK QVEAITKQIE AEVDALAPKN KEEEEKEKEK