ID   BOD1_XENLA              Reviewed;         169 AA.
AC   Q6DFL2;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Biorientation of chromosomes in cell division protein 1;
DE   AltName: Full=Biorientation defective protein 1;
DE   AltName: Full=Protein FAM44B;
GN   Name=bod1; Synonyms=fam44b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper chromosome biorientation through the
CC       detection or correction of syntelic attachments in mitotic spindles.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Chromosome, centromere, kinetochore
CC       {ECO:0000250}. Note=Localizes at the centrosomes throughout the cell
CC       cycle, only dissociating during cytokinesis. Localizes at the
CC       kinetochore from prometaphase until anaphase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BOD1 family. {ECO:0000305}.
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DR   EMBL; BC076724; AAH76724.1; -; mRNA.
DR   RefSeq; NP_001086501.1; NM_001093032.1.
DR   AlphaFoldDB; Q6DFL2; -.
DR   SMR; Q6DFL2; -.
DR   DNASU; 446336; -.
DR   GeneID; 446336; -.
DR   KEGG; xla:446336; -.
DR   CTD; 446336; -.
DR   Xenbase; XB-GENE-6079024; bod1.L.
DR   OrthoDB; 1333373at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 446336; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR026955; Bod1-like.
DR   PANTHER; PTHR31532; PTHR31532; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Centromere; Chromosome; Cytoplasm; Cytoskeleton;
KW   Kinetochore; Mitosis; Reference proteome.
FT   CHAIN           1..169
FT                   /note="Biorientation of chromosomes in cell division
FT                   protein 1"
FT                   /id="PRO_0000187031"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..161
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   169 AA;  18343 MW;  F88E03DD3CF75CAE CRC64;
     MAESGSGTSG GSSSVGGVSN PASLAPGDSQ LIALIVEQLK SRGQFDGFRR DCLADVDTKP
     AYQNLRQKVD NFVSTHLDKQ EWNADMNKNQ LRNGLRQSVI QSGMLEAGVD RIISQVVDPK
     LNHIFRPQIE KAIHEYLTAQ TKEDSAPPLP PGPPEPQEQE PPEPSQSVS