ABRB_ECOLI
ID ABRB_ECOLI Reviewed; 348 AA.
AC P75747;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 2.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Putative regulator AbrB;
DE AltName: Full=AidB regulator;
GN Name=abrB; Synonyms=ybgN; OrderedLocusNames=b0715, JW5097;
GN ORFNames=ECK0704;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP POSSIBLE FUNCTION.
RX PubMed=8002588; DOI=10.1128/jb.176.24.7638-7645.1994;
RA Volkert M.R., Hajec L.I., Matijasevic Z., Fang F.C., Prince R.;
RT "Induction of the Escherichia coli aidB gene under oxygen-limiting
RT conditions requires a functional rpoS (katF) gene.";
RL J. Bacteriol. 176:7638-7645(1994).
RN [5]
RP SUBCELLULAR LOCATION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Seems to be involved in the regulation of AidB.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:15919996}.
CC -!- SIMILARITY: Belongs to the AbrB family. {ECO:0000305}.
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DR EMBL; U00096; AAC73809.2; -; Genomic_DNA.
DR EMBL; AP009048; BAA35379.2; -; Genomic_DNA.
DR PIR; B64807; B64807.
DR RefSeq; NP_415243.4; NC_000913.3.
DR RefSeq; WP_001336221.1; NZ_SSZK01000033.1.
DR AlphaFoldDB; P75747; -.
DR SMR; P75747; -.
DR BioGRID; 4259923; 2.
DR STRING; 511145.b0715; -.
DR PaxDb; P75747; -.
DR PRIDE; P75747; -.
DR EnsemblBacteria; AAC73809; AAC73809; b0715.
DR EnsemblBacteria; BAA35379; BAA35379; BAA35379.
DR GeneID; 945321; -.
DR KEGG; ecj:JW5097; -.
DR KEGG; eco:b0715; -.
DR PATRIC; fig|1411691.4.peg.1558; -.
DR EchoBASE; EB3094; -.
DR eggNOG; COG3180; Bacteria.
DR HOGENOM; CLU_050210_0_1_6; -.
DR InParanoid; P75747; -.
DR OMA; MQYVRVV; -.
DR PhylomeDB; P75747; -.
DR BioCyc; EcoCyc:G6384-MON; -.
DR PRO; PR:P75747; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR InterPro; IPR017516; AbrB_dup.
DR InterPro; IPR007820; AbrB_fam.
DR PANTHER; PTHR38457; PTHR38457; 1.
DR Pfam; PF05145; AbrB; 1.
DR PIRSF; PIRSF038991; Protein_AbrB; 1.
DR TIGRFAMs; TIGR03082; Gneg_AbrB_dup; 2.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..348
FT /note="Putative regulator AbrB"
FT /id="PRO_0000064432"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 348 AA; 36884 MW; 9A667EA6321B0B8A CRC64;
MPVLQWGMLC VLSLLLSIGF LAVHLPAALL LGPMIAGIIF SMRGITLQLP RSAFLAAQAI
LGCMIAQNLT GSILTTLAVN WPIVLAILLV TLLSSAIVGW LLVRYSSLPG NTGAWGSSPG
GAAAMVAMAQ DYGADIRLVA FMQYLRVLFV AGAAVLVTRM MLGDNAEAVN QHIVWFPPVS
INLLLTILLA VVAGTVGCLL RLPSGTMLIP MLAGAVLQSG QLITIELPEW LLAMAYMAIG
WRIGLGFDKQ ILLRALRPLP QILLSIFALL AICAGMAWGL TRFMHIDFMT AYLATSPGGL
DTVAVIAAGS NADMALIMAM QTLRLFSILL TGPAIARFIS TYAPKRSA
