BOLA1_BOVIN
ID BOLA1_BOVIN Reviewed; 135 AA.
AC Q3T138;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=BolA-like protein 1;
GN Name=BOLA1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly
CC factor that facilitates (Fe-S) cluster insertion into a subset of
CC mitochondrial proteins (By similarity). Probably acts together with the
CC monothiol glutaredoxin GLRX5. May protect cells against oxidative
CC stress (By similarity). {ECO:0000250|UniProtKB:Q3E793,
CC ECO:0000250|UniProtKB:Q9Y3E2}.
CC -!- SUBUNIT: Interacts with GLRX5. {ECO:0000250|UniProtKB:Q9Y3E2}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9Y3E2}.
CC -!- SIMILARITY: Belongs to the BolA/IbaG family. {ECO:0000305}.
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DR EMBL; BC102140; AAI02141.1; -; mRNA.
DR RefSeq; NP_001029524.1; NM_001034352.1.
DR AlphaFoldDB; Q3T138; -.
DR SMR; Q3T138; -.
DR STRING; 9913.ENSBTAP00000043360; -.
DR PaxDb; Q3T138; -.
DR PRIDE; Q3T138; -.
DR Ensembl; ENSBTAT00000007946; ENSBTAP00000043360; ENSBTAG00000006050.
DR GeneID; 509530; -.
DR KEGG; bta:509530; -.
DR CTD; 51027; -.
DR VEuPathDB; HostDB:ENSBTAG00000006050; -.
DR VGNC; VGNC:50092; BOLA1.
DR eggNOG; KOG2313; Eukaryota.
DR GeneTree; ENSGT00510000048165; -.
DR HOGENOM; CLU_109462_3_0_1; -.
DR InParanoid; Q3T138; -.
DR OMA; CLGGFGK; -.
DR OrthoDB; 1603661at2759; -.
DR TreeFam; TF354266; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000006050; Expressed in choroid plexus and 109 other tissues.
DR GO; GO:1990229; C:iron-sulfur cluster assembly complex; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR Gene3D; 3.30.300.90; -; 1.
DR InterPro; IPR002634; BolA.
DR InterPro; IPR036065; BolA-like_sf.
DR Pfam; PF01722; BolA; 1.
DR SUPFAM; SSF82657; SSF82657; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion; Phosphoprotein; Reference proteome.
FT CHAIN 1..135
FT /note="BolA-like protein 1"
FT /id="PRO_0000245499"
FT REGION 114..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 81
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9D8S9"
SQ SEQUENCE 135 AA; 14355 MW; 78B58DED67946BFD CRC64;
MLSGQLVVRL FSMASRVCMS RGSAGSGVIG PVEAAIRTKL EQALNPEVLE LRNESGGHAV
PPGSETHFRV AVVSSRFEGL SPLQRHRLVH AALSEELAGP VHALAIQART PAQWKENPQL
DTSPACLGGS KKSRN