BOLA1_PONAB
ID BOLA1_PONAB Reviewed; 137 AA.
AC Q5RCE5;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=BolA-like protein 1;
GN Name=BOLA1;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly
CC factor that facilitates (Fe-S) cluster insertion into a subset of
CC mitochondrial proteins (By similarity). Probably acts together with the
CC monothiol glutaredoxin GLRX5. May protect cells against oxidative
CC stress (By similarity). {ECO:0000250|UniProtKB:Q3E793,
CC ECO:0000250|UniProtKB:Q9Y3E2}.
CC -!- SUBUNIT: Interacts with GLRX5. {ECO:0000250|UniProtKB:Q9Y3E2}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9Y3E2}.
CC -!- SIMILARITY: Belongs to the BolA/IbaG family. {ECO:0000305}.
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DR EMBL; CR858326; CAH90562.1; -; mRNA.
DR RefSeq; NP_001125298.1; NM_001131826.1.
DR AlphaFoldDB; Q5RCE5; -.
DR SMR; Q5RCE5; -.
DR STRING; 9601.ENSPPYP00000001068; -.
DR Ensembl; ENSPPYT00000048740; ENSPPYP00000043835; ENSPPYG00000040309.
DR GeneID; 100172197; -.
DR KEGG; pon:100172197; -.
DR CTD; 51027; -.
DR eggNOG; KOG2313; Eukaryota.
DR GeneTree; ENSGT00510000048165; -.
DR HOGENOM; CLU_109462_3_0_1; -.
DR InParanoid; Q5RCE5; -.
DR OrthoDB; 1603661at2759; -.
DR TreeFam; TF354266; -.
DR Proteomes; UP000001595; Chromosome 1.
DR GO; GO:1990229; C:iron-sulfur cluster assembly complex; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR Gene3D; 3.30.300.90; -; 1.
DR InterPro; IPR002634; BolA.
DR InterPro; IPR036065; BolA-like_sf.
DR Pfam; PF01722; BolA; 1.
DR SUPFAM; SSF82657; SSF82657; 1.
PE 2: Evidence at transcript level;
KW Mitochondrion; Phosphoprotein; Reference proteome.
FT CHAIN 1..137
FT /note="BolA-like protein 1"
FT /id="PRO_0000201235"
FT REGION 114..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 81
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9D8S9"
SQ SEQUENCE 137 AA; 14187 MW; 8BEAEBBD5E467180 CRC64;
MLSGRLVPGL VSMAGRVCLC QGSAGSGAVG PVEAAIRTKL EQALSPEVLE LRNESGGHAV
PPGSETHFRV AVVSSRFEGL SPLQRHRLIH AALAEELAGP VHALAIQART PAQWGENSQL
DTSPPCLGGN KKTLGTP