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BOLL_MACFA
ID   BOLL_MACFA              Reviewed;         283 AA.
AC   Q8WP23;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2004, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Protein boule-like;
GN   Name=BOLL; ORFNames=QtsA-21032;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
CC   -!- FUNCTION: Probable RNA-binding protein, which may be required during
CC       spermatogenesis. May act by binding to the 3'-UTR of mRNAs and
CC       regulating their translation (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with DAZ1 and DAZL. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRM DAZ family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01238}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB72085.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AB074454; BAB72085.1; ALT_SEQ; mRNA.
DR   AlphaFoldDB; Q8WP23; -.
DR   SMR; Q8WP23; -.
DR   STRING; 9541.XP_005573893.1; -.
DR   eggNOG; KOG0118; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR037366; BOULE/DAZ.
DR   InterPro; IPR043628; DAZ_dom.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR11176; PTHR11176; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS51890; DAZ; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Developmental protein; Differentiation; Reference proteome;
KW   RNA-binding; Spermatogenesis; Translation regulation.
FT   CHAIN           1..283
FT                   /note="Protein boule-like"
FT                   /id="PRO_0000081495"
FT   DOMAIN          33..110
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          160..184
FT                   /note="DAZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01238"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  31267 MW;  6381EBD2583FFCF6 CRC64;
     MQTDSLSPSP NPVSPVPLNN PTSAPRYGTV IPNRIFVGGI DFKTNESDLR KFFSQYGSVK
     EVKIVNDRAG VSKGYGFVTF ETQEDAQKIL QEAEKLNYKD KKLNIGPAIR KQQVGIPRSS
     IMPAAGTMYL TTSTGYPYTY HNGVAYFHTP EVTSVPPPWP SRSVCSSPVM VAQPIYQQPA
     YHYQATAQYL PGQWQWSVPQ PPASSAPFLY LQPSEVIYQP VEIAQDGGCV PPPLSLMETS
     VPEPYSDHGV QATYHQVYAP SAISMPAPVM QPEPIKTVWS IHY
 
 
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