ID   BOP1_CAEBR              Reviewed;         671 AA.
AC   A8XYW9;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Ribosome biogenesis protein BOP1 homolog {ECO:0000255|HAMAP-Rule:MF_03027};
GN   ORFNames=CBG20902;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC       the large ribosomal subunit. {ECO:0000255|HAMAP-Rule:MF_03027}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC       Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03027}.
CC   -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC       {ECO:0000255|HAMAP-Rule:MF_03027}.
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DR   EMBL; HE600928; CAP37836.1; -; Genomic_DNA.
DR   RefSeq; XP_002631703.1; XM_002631657.1.
DR   AlphaFoldDB; A8XYW9; -.
DR   SMR; A8XYW9; -.
DR   STRING; 6238.CBG20902; -.
DR   PRIDE; A8XYW9; -.
DR   EnsemblMetazoa; CBG20902.1; CBG20902.1; WBGene00039807.
DR   GeneID; 8573702; -.
DR   KEGG; cbr:CBG_20902; -.
DR   CTD; 8573702; -.
DR   WormBase; CBG20902; CBP04933; WBGene00039807; -.
DR   eggNOG; KOG0650; Eukaryota.
DR   HOGENOM; CLU_011390_2_0_1; -.
DR   InParanoid; A8XYW9; -.
DR   OMA; MRPAKGE; -.
DR   OrthoDB; 759498at2759; -.
DR   Proteomes; UP000008549; Chromosome II.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070545; C:PeBoW complex; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IBA:GO_Central.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_03027; BOP1; 1.
DR   InterPro; IPR028598; BOP1/Erb1.
DR   InterPro; IPR012953; BOP1_N_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR17605; PTHR17605; 1.
DR   Pfam; PF08145; BOP1NT; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM01035; BOP1NT; 1.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing;
KW   WD repeat.
FT   CHAIN           1..671
FT                   /note="Ribosome biogenesis protein BOP1 homolog"
FT                   /id="PRO_0000370406"
FT   REPEAT          339..381
FT                   /note="WD 1"
FT   REPEAT          383..422
FT                   /note="WD 2"
FT   REPEAT          424..455
FT                   /note="WD 3"
FT   REPEAT          456..497
FT                   /note="WD 4"
FT   REPEAT          500..538
FT                   /note="WD 5"
FT   REPEAT          584..623
FT                   /note="WD 6"
FT   REPEAT          640..671
FT                   /note="WD 7"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..36
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   671 AA;  76989 MW;  84E653CAB02388CB CRC64;
     MASTSTALPV RTKRKLENGK KKPKTPKDEF GEKLDVKPVI KPADEYDYDS SDEEDLRNTI
     GNIPIQWYDD EDHIGYDKFG EKIAKPAKKG EIETFLEKME DPDYWRKVFD KQTGTDVKLT
     DEQIEKIHNI ASGKYPTIGY NPYEPFLDIY SSQKEIHPID NRPEPKARFI PSKDEMRMVS
     RMVHAIKMGW AKGPKNKKEE PKAYDLWASE DALDNVTKSQ LSRMRVHMPA PKVALPTHAE
     SYNPPEEYLF DDEERKKWEE AEKEDRVLNF MPSKYDALRK VPQYDKFITE RFERCLDLYL
     APRQRKMRIH ADPTDLLPDL PNPNDLRPFP TTLAFYMRGH TGQVRAISVE PVHGELLASG
     GEDGTVRIWM MATGRCIKTF QMDGEVTSVA FSPVADRTLL AVAYEGKYVA ILNTGCGDRL
     HVQQTETLLA ETPTESQEDG AIVTWRKSKD KLVLKMPNEV RQVTWHAKGD YFASVAIDDI
     AKSVYVHQMS KAKSQCPFQK RKGHVQAVTF HPTQARLFVA TKIHVREYDL ARCVLVKKLI
     TGCKHISSMA TDANGENLFL GGLDRRFCWM DLQMGNKPWK KLKHHTAAVR SVAYHKKYPL
     LATVSDDGTA MVYYARIYSD FSKDNELYPV KRLRAHERTS NDLCMLHTTW HPTQPWLITT
     GADGTIALFT Y