BOP1_CHLRE
ID BOP1_CHLRE Reviewed; 797 AA.
AC A8ID74;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 2.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Ribosome biogenesis protein BOP1 homolog {ECO:0000255|HAMAP-Rule:MF_03027};
GN ORFNames=CHLREDRAFT_111274;
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503, and cw92;
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC the large ribosomal subunit. {ECO:0000255|HAMAP-Rule:MF_03027}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000255|HAMAP-
CC Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000255|HAMAP-Rule:MF_03027}.
CC -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC {ECO:0000255|HAMAP-Rule:MF_03027}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EDP06418.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; DS496115; EDP06418.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; A8ID74; -.
DR SMR; A8ID74; -.
DR STRING; 3055.EDP06418; -.
DR PaxDb; A8ID74; -.
DR PRIDE; A8ID74; -.
DR ProMEX; A8ID74; -.
DR eggNOG; KOG0650; Eukaryota.
DR HOGENOM; CLU_011390_2_0_1; -.
DR InParanoid; A8ID74; -.
DR OrthoDB; 759498at2759; -.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_03027; BOP1; 1.
DR InterPro; IPR028598; BOP1/Erb1.
DR InterPro; IPR012953; BOP1_N_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR17605; PTHR17605; 1.
DR Pfam; PF08145; BOP1NT; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01035; BOP1NT; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Nucleus; Repeat; Ribosome biogenesis; rRNA processing; WD repeat.
FT CHAIN 1..797
FT /note="Ribosome biogenesis protein BOP1 homolog"
FT /id="PRO_0000370413"
FT REPEAT 462..502
FT /note="WD 1"
FT REPEAT 504..544
FT /note="WD 2"
FT REPEAT 581..623
FT /note="WD 3"
FT REPEAT 626..664
FT /note="WD 4"
FT REPEAT 667..706
FT /note="WD 5"
FT REPEAT 710..749
FT /note="WD 6"
FT REPEAT 766..797
FT /note="WD 7"
FT REGION 22..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 797 AA; 86098 MW; D5ADDB8CDAB7CB0C CRC64;
MHIISAIYSA RVQNCAAPTQ PLVPSCQTHS AASHTPPGPS ARLPSPARPE ASTRTQGKSH
AGAAAAAVEG TAAPEDEAAD NSSEEDAGPG SHGEGAGEGG GSGTWPGNGG GPQPIHRCAG
SVVAGATRGG CVAATRLYLA AVQPSGGLSI CANTKPRAGP DPGSDSSEDE RPNRNTVGNV
PLVWYKDEEH IGYDIEGARI TKAQRKDRLQ QLLDRNDSKK ALRTIYDPYN DEEVTLSKEE
LAMVMRIRAG QFPHLEVNPH ETEHTWFTDP RDAEVMPIVD RPEPKSRFVP SKWEEQKIVK
LVRAIRKGWI KKTPEQEEEE RAAGPPAYLL WADDGLTDEA AAKAGSGLTY IPAPKLQLPG
HADSYNPPAE YLPTEEEVAA WQMADPEDRP KALPQAFTSL RAVPAYTDFI KERFERCLDL
YLCPRVRRKR LDIKSPEQLV PQLPKPRDLQ PFPTTLALAY EGHMGPVASI APDPWTGQWL
LSGGQDGTLR LWEVRTGRCW RTWVLEGPVS AVAWCPQAGL RLVSAAVGNC VVLLPSGTGP
EEAEEAAAEA LRVRGPGRGG GRWVRGGPEE ASSSGAGLAV RLRFPVRSLA WHGRGDYFAS
VAPTGNTQAV VVHQLSKRAS QNPFRKNRGR VVRVAFHPTK PFFFVATQNH VRVYNLAKQA
LAKKLLGGGG VLSCLALHPG GDHVLVGSDD KRVAWYDLDL STKPYKALRY HSAPPRAVAF
HRSYPLFASA ADDGTVQVFH GMVYADLLTN PLIVPVKILR GGHTVTASEG VADCAFHPTQ
PWIFTAGADS KILLYCN
