ID   BOPA_BURP0              Reviewed;         512 AA.
AC   A3P6Y8;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Effector protein BopA;
GN   Name=bopA; OrderedLocusNames=BURPS1106A_A2064;
OS   Burkholderia pseudomallei (strain 1106a).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=357348;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1106a;
RX   PubMed=20333227; DOI=10.1093/gbe/evq003;
RA   Losada L., Ronning C.M., DeShazer D., Woods D., Fedorova N., Kim H.S.,
RA   Shabalina S.A., Pearson T.R., Brinkac L., Tan P., Nandi T., Crabtree J.,
RA   Badger J., Beckstrom-Sternberg S., Saqib M., Schutzer S.E., Keim P.,
RA   Nierman W.C.;
RT   "Continuing evolution of Burkholderia mallei through genome reduction and
RT   large-scale rearrangements.";
RL   Genome Biol. Evol. 2:102-116(2010).
CC   -!- FUNCTION: Plays a role in mediating bacterial evasion from the host
CC       autophagic pathway. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Secreted via the bsa
CC       type III secretion system. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BopA/IcsB family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000573; ABN93647.1; -; Genomic_DNA.
DR   RefSeq; WP_004536698.1; NC_009078.1.
DR   AlphaFoldDB; A3P6Y8; -.
DR   EnsemblBacteria; ABN93647; ABN93647; BURPS1106A_A2064.
DR   GeneID; 56530068; -.
DR   KEGG; bpl:BURPS1106A_A2064; -.
DR   HOGENOM; CLU_531773_0_0_4; -.
DR   OMA; MSKFICQ; -.
DR   Proteomes; UP000006738; Chromosome II.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   Gene3D; 4.10.1330.10; -; 1.
DR   InterPro; IPR011070; Globular_prot_asu/bsu.
DR   InterPro; IPR015203; SptP_N.
DR   InterPro; IPR044899; SptP_N_sf.
DR   Pfam; PF09119; SicP-binding; 1.
DR   SUPFAM; SSF56568; SSF56568; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Secreted; Virulence.
FT   CHAIN           1..512
FT                   /note="Effector protein BopA"
FT                   /id="PRO_0000344023"
FT   COILED          347..377
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   512 AA;  56824 MW;  4CF9423A33543044 CRC64;
     MINVGAFVAS ARSGARVVVG GDARGPVVSA ARLGMKERLF AFLAHVPLLK HCDAVRRYAE
     QVRMENRRSL EVFVLALSKR YGPEGAKAAF DYGARRDGAP LDQRRVRNMV SIAEHFHGTG
     DAKPLARQMV FRSWECRGLD HPGHASLTIK NQADADAGRH VYEHVSWWPN QRLGSKEHFD
     RIKPKTLDGY RIDKRSEISS ATEQRLREGD AARRKILADG FKYANQDERY DARFFPRAGQ
     KLDKDAEWGL SARKVYFPAI GFNHDRRDTD RPRAFVLFGL NEAAMLRDAR TVKEGAKSGE
     LKYRMISKKE NCASMALRVL RAGGAEHFVP YTAAWISEDP NHAHAYALAV QARIDALNQR
     RADVERRCER LRDSASVRQA WRAFSEAGGA SASPLAEDAG RGRASAHMRQ ARLDEHAREV
     ERIGAYFAEL SAGRSGKHRD RADAALADAM KRCAPSARDD VAALTRKASV LVETLGRHLD
     APPPSDSSAL RRLAAHAMIG RIEAFMAAAI AA