ID   BOPA_BURTA              Reviewed;         512 AA.
AC   Q2T703;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Effector protein BopA;
GN   Name=bopA; OrderedLocusNames=BTH_II0849;
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS   E264).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- FUNCTION: Plays a role in mediating bacterial evasion from the host
CC       autophagic pathway. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Secreted via the bsa
CC       type III secretion system. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BopA/IcsB family. {ECO:0000305}.
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DR   EMBL; CP000085; ABC35495.1; -; Genomic_DNA.
DR   RefSeq; WP_011401050.1; NZ_CP008786.1.
DR   AlphaFoldDB; Q2T703; -.
DR   EnsemblBacteria; ABC35495; ABC35495; BTH_II0849.
DR   KEGG; bte:BTH_II0849; -.
DR   HOGENOM; CLU_531773_0_0_4; -.
DR   OMA; MSKFICQ; -.
DR   OrthoDB; 384699at2; -.
DR   Proteomes; UP000001930; Chromosome II.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   Gene3D; 4.10.1330.10; -; 1.
DR   InterPro; IPR011070; Globular_prot_asu/bsu.
DR   InterPro; IPR015203; SptP_N.
DR   InterPro; IPR044899; SptP_N_sf.
DR   Pfam; PF09119; SicP-binding; 1.
DR   SUPFAM; SSF56568; SSF56568; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Secreted; Virulence.
FT   CHAIN           1..512
FT                   /note="Effector protein BopA"
FT                   /id="PRO_0000344026"
FT   REGION          388..415
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          347..374
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   512 AA;  56487 MW;  6A1C701A9D8697DD CRC64;
     MISVGAFAAC ARQGERVVVG DGARGPAVSV ARLGMKERLF AFLSHVPLLK HCDAVRRYAE
     QVRTENRRTL EVFVLALSKR YGPEGAKAAF DYGARRDGAP LDQRRVRNMV SIAEHFHGTG
     DAKPMARQIV FRSWECQGLD HPGHASLTIK NQADADAGRH VYEHVSWWPD RKLGGKENVN
     RVEPKMQDGY RIDKRSEIST TTEQRLREGD AARRKILADG FKYANEDERH DARFFPRAGQ
     KLDKDAQWGL SARKVYFPAI GFNHDKRDTD GPRAFVLFGL NEAAMLRDAR TVKEGAKTGE
     LKFQMISKKE NCASMALRVL RAGGAEHFVP FTAAWISEDP NRAHAYALAV QARIDALNQQ
     RADVERHCAR LRGSASVRQA WRAFSEAGNA SGSPLADQAG RGRASAHTRQ ARLDEHAREV
     ERIGASFAEL SAGRSGKHRD RADADLADAM KRCAPSARDD VAALTRKASV LVETLGRHLD
     APPPSDSSAL RMLAAHAMIG RIEAFMADAI AA