ID   BORA_RAT                Reviewed;         534 AA.
AC   Q5M864;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Protein aurora borealis;
GN   Name=Bora;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Thymus;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Required for the activation of AURKA at the onset of mitosis.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with AURKA. {ECO:0000250}.
CC   -!- PTM: Phosphorylated by AURKA. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BORA family. {ECO:0000305}.
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DR   EMBL; BC088204; AAH88204.1; -; mRNA.
DR   RefSeq; NP_001014019.1; NM_001013997.1.
DR   AlphaFoldDB; Q5M864; -.
DR   STRING; 10116.ENSRNOP00000035098; -.
DR   PaxDb; Q5M864; -.
DR   Ensembl; ENSRNOT00000039344; ENSRNOP00000035098; ENSRNOG00000024798.
DR   GeneID; 306102; -.
DR   KEGG; rno:306102; -.
DR   UCSC; RGD:1309522; rat.
DR   CTD; 79866; -.
DR   RGD; 1309522; Bora.
DR   eggNOG; ENOG502S85H; Eukaryota.
DR   GeneTree; ENSGT00390000013790; -.
DR   HOGENOM; CLU_038376_0_0_1; -.
DR   InParanoid; Q5M864; -.
DR   OMA; STWIKEP; -.
DR   OrthoDB; 539473at2759; -.
DR   PhylomeDB; Q5M864; -.
DR   TreeFam; TF329674; -.
DR   Reactome; R-RNO-2565942; Regulation of PLK1 Activity at G2/M Transition.
DR   PRO; PR:Q5M864; -.
DR   Proteomes; UP000002494; Chromosome 15.
DR   Bgee; ENSRNOG00000024798; Expressed in thymus and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0072687; C:meiotic spindle; ISO:RGD.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0019901; F:protein kinase binding; ISO:RGD.
DR   GO; GO:0032147; P:activation of protein kinase activity; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007088; P:regulation of mitotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0060236; P:regulation of mitotic spindle organization; ISS:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
DR   InterPro; IPR023252; Aurora_borealis_protein.
DR   PANTHER; PTHR14728; PTHR14728; 1.
DR   Pfam; PF15280; BORA_N; 1.
DR   PRINTS; PR02038; AURORABORA.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Methylation; Mitosis; Phosphoprotein;
KW   Reference proteome.
FT   CHAIN           1..534
FT                   /note="Protein aurora borealis"
FT                   /id="PRO_0000273207"
FT   REGION          114..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          206..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..141
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         183
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PGQ7"
FT   MOD_RES         191
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PGQ7"
FT   MOD_RES         250
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PGQ7"
FT   MOD_RES         305
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BS90"
FT   MOD_RES         311
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BS90"
FT   MOD_RES         316
FT                   /note="Omega-N-methylarginine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8BS90"
SQ   SEQUENCE   534 AA;  57633 MW;  141CEDE7DB4D9921 CRC64;
     MGDVSELKMQ ITPATPGRIP VLNPFESPSD YSNLHEQTLA SPSVFKSTKL PTPGEFRWSI
     DQLAVINPVE IDPEEIHRQA SYLSLSRIDK DVEDKRQKAI EEFFTKDVIV PSPWTDHDGK
     QPSELHPSKC LTSNGDSPVG KKPSLPSQKC NAACQTLLSL PVDFNLEAVL GDYFRADDSV
     DQSPGNLSSS SLRRKLFLDV NGSISDSLPS ASPRSPPNSA RGSLEGQFSS SPIQNNAKKY
     SLGSLTTSPS AICSPTFSPI ALQVGKTPLS EHRKFTFHSP EASSGGSSTG IANPSIRSPY
     IDGCSPIKNW SPRGLRGGPQ YLSSLIRVPF ALETHSEDEE DNVSSTDVAA LGTNAVAAPL
     QQLDCEPLAC GDPFVVSAMP VTQSQSSTCE KDLGLLGDFE SERDHDTVDM VDPIDTADES
     TWIKEPVGNG NSPMAEFVSG IAFSIENSHM CMSPLAESSV LPCESSNVQM DSGYNTQTCG
     SNITDIVGTE SYCKENVTQS FEAQMKPQVN NIKQDHTVQR CWMKTTSPSQ CSSL