ID   BORC5_DANRE             Reviewed;         207 AA.
AC   Q5XIX8;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=BLOC-1-related complex subunit 5 {ECO:0000305};
GN   Name=borcs5 {ECO:0000250|UniProtKB:Q969J3};
GN   ORFNames=zgc:92915 {ECO:0000312|EMBL:AAH83541.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As part of a BORC-like complex may play a role in lysosomes
CC       movement and localization at the cell periphery. Associated with the
CC       cytosolic face of lysosomes, this complex may couple lysosomes to
CC       microtubule plus-end-directed kinesin motor.
CC       {ECO:0000250|UniProtKB:Q969J3}.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q969J3};
CC       Lipid-anchor {ECO:0000250|UniProtKB:Q969J3}; Cytoplasmic side
CC       {ECO:0000250|UniProtKB:Q969J3}.
CC   -!- SIMILARITY: Belongs to the BORCS5 family. {ECO:0000305}.
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DR   EMBL; BC083541; AAH83541.1; -; mRNA.
DR   RefSeq; NP_001007053.1; NM_001007052.2.
DR   AlphaFoldDB; Q5XIX8; -.
DR   SMR; Q5XIX8; -.
DR   STRING; 7955.ENSDARP00000087790; -.
DR   PaxDb; Q5XIX8; -.
DR   DNASU; 449650; -.
DR   Ensembl; ENSDART00000093358; ENSDARP00000087790; ENSDARG00000077830.
DR   GeneID; 449650; -.
DR   KEGG; dre:449650; -.
DR   CTD; 118426; -.
DR   ZFIN; ZDB-GENE-041010-83; borcs5.
DR   eggNOG; KOG4515; Eukaryota.
DR   GeneTree; ENSGT00390000015016; -.
DR   InParanoid; Q5XIX8; -.
DR   OrthoDB; 1446665at2759; -.
DR   PhylomeDB; Q5XIX8; -.
DR   TreeFam; TF316379; -.
DR   PRO; PR:Q5XIX8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 25.
DR   Bgee; ENSDARG00000077830; Expressed in early embryo and 25 other tissues.
DR   ExpressionAtlas; Q5XIX8; baseline.
DR   GO; GO:0099078; C:BORC complex; ISS:UniProtKB.
DR   GO; GO:0098574; C:cytoplasmic side of lysosomal membrane; ISS:UniProtKB.
DR   GO; GO:0031224; C:intrinsic component of membrane; ISS:UniProtKB.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IBA:GO_Central.
DR   GO; GO:0032418; P:lysosome localization; ISS:UniProtKB.
DR   GO; GO:0072384; P:organelle transport along microtubule; ISS:UniProtKB.
DR   GO; GO:1903744; P:positive regulation of anterograde synaptic vesicle transport; IBA:GO_Central.
DR   InterPro; IPR018780; TBORCS5.
DR   PANTHER; PTHR31634; PTHR31634; 1.
DR   Pfam; PF10158; LOH1CR12; 1.
PE   2: Evidence at transcript level;
KW   Lipoprotein; Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..207
FT                   /note="BLOC-1-related complex subunit 5"
FT                   /id="PRO_0000318599"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   207 AA;  23544 MW;  FC4A8D8396729CAD CRC64;
     MGAEQSGDAD HKHSDFSASV VPSPAKHRAK MDDIVVVAQG TQSLRNIHND PDVIKLQEIP
     TFQPLLKGVL SGQTSPSTVC LEKLDSAQVL QLCVRYQDHL HQCAEAVAFD QNALVKRIKE
     MDLSVEALFS IMQERQKRYA KYAEQIQKVN EMSMILRRIQ MGIDQTVPLM ERLNNMLPES
     LFWMLPMEHI TFALDCLSYA WIRCFLA