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BORC5_XENTR
ID   BORC5_XENTR             Reviewed;         196 AA.
AC   A8E5U3;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=BLOC-1-related complex subunit 5 {ECO:0000305};
GN   Name=borcs5 {ECO:0000250|UniProtKB:Q969J3};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tail;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As part of a BORC-like complex may play a role in lysosomes
CC       movement and localization at the cell periphery. Associated with the
CC       cytosolic face of lysosomes, this complex may couple lysosomes to
CC       microtubule plus-end-directed kinesin motor.
CC       {ECO:0000250|UniProtKB:Q969J3}.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q969J3};
CC       Lipid-anchor {ECO:0000250|UniProtKB:Q969J3}; Cytoplasmic side
CC       {ECO:0000250|UniProtKB:Q969J3}.
CC   -!- SIMILARITY: Belongs to the BORCS5 family. {ECO:0000305}.
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DR   EMBL; BC153719; AAI53720.1; -; mRNA.
DR   RefSeq; NP_001106433.1; NM_001112962.1.
DR   RefSeq; XP_012813950.1; XM_012958496.2.
DR   AlphaFoldDB; A8E5U3; -.
DR   SMR; A8E5U3; -.
DR   STRING; 8364.ENSXETP00000022104; -.
DR   PaxDb; A8E5U3; -.
DR   DNASU; 100127605; -.
DR   GeneID; 100127605; -.
DR   KEGG; xtr:100127605; -.
DR   CTD; 118426; -.
DR   Xenbase; XB-GENE-940511; borcs5.
DR   eggNOG; KOG4515; Eukaryota.
DR   HOGENOM; CLU_064176_1_0_1; -.
DR   InParanoid; A8E5U3; -.
DR   OrthoDB; 1446665at2759; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   ExpressionAtlas; A8E5U3; baseline.
DR   GO; GO:0099078; C:BORC complex; ISS:UniProtKB.
DR   GO; GO:0098574; C:cytoplasmic side of lysosomal membrane; ISS:UniProtKB.
DR   GO; GO:0031224; C:intrinsic component of membrane; ISS:UniProtKB.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IBA:GO_Central.
DR   GO; GO:0032418; P:lysosome localization; ISS:UniProtKB.
DR   GO; GO:0072384; P:organelle transport along microtubule; ISS:UniProtKB.
DR   GO; GO:1903744; P:positive regulation of anterograde synaptic vesicle transport; IBA:GO_Central.
DR   InterPro; IPR018780; TBORCS5.
DR   PANTHER; PTHR31634; PTHR31634; 1.
DR   Pfam; PF10158; LOH1CR12; 1.
PE   2: Evidence at transcript level;
KW   Lipoprotein; Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..196
FT                   /note="BLOC-1-related complex subunit 5"
FT                   /id="PRO_0000318601"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  22096 MW;  BCF9D9560CE9BF19 CRC64;
     MGAEQSSEGD LRQNDLSSSV SPSPAKQKAK MDDIVVVAPG TQSLRNVSKD PEVIKLQEIP
     TFQPLLKGLL SGQTSPTNVR LERLDSPQVL QLCVRYQEHL HQCAEAVSFD QNALVKRIKE
     MDSSVDGLYS LMQERQKRFA KYAEQIQKVN EMSAILRRIQ MGIDQTVPLM EKLNIMLPEG
     ERLEPFCMSP DRESKP
 
 
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