BORC7_BOVIN
ID BORC7_BOVIN Reviewed; 105 AA.
AC Q2KIB7;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2009, sequence version 2.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=BLOC-1-related complex subunit 7 {ECO:0000305};
GN Name=BORCS7 {ECO:0000250|UniProtKB:Q96B45};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: As part of the BORC complex may play a role in lysosomes
CC movement and localization at the cell periphery. Associated with the
CC cytosolic face of lysosomes, the BORC complex may recruit ARL8B and
CC couple lysosomes to microtubule plus-end-directed kinesin motor.
CC {ECO:0000250|UniProtKB:Q96B45}.
CC -!- SUBUNIT: Component of the BLOC-one-related complex (BORC) which is
CC composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and
CC SNAPIN. {ECO:0000250|UniProtKB:Q96B45}.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q96B45}.
CC -!- SIMILARITY: Belongs to the BORCS7 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI12698.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC112697; AAI12698.1; ALT_INIT; mRNA.
DR RefSeq; XP_002698544.2; XM_002698498.4.
DR RefSeq; XP_015325077.1; XM_015469591.1.
DR AlphaFoldDB; Q2KIB7; -.
DR SMR; Q2KIB7; -.
DR STRING; 9913.ENSBTAP00000028310; -.
DR PaxDb; Q2KIB7; -.
DR GeneID; 613274; -.
DR KEGG; bta:613274; -.
DR CTD; 119032; -.
DR eggNOG; ENOG502S2QS; Eukaryota.
DR HOGENOM; CLU_150749_1_0_1; -.
DR OrthoDB; 1626208at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0099078; C:BORC complex; ISS:UniProtKB.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032143; BORCS7.
DR PANTHER; PTHR31397; PTHR31397; 1.
DR Pfam; PF16088; BORCS7; 1.
PE 3: Inferred from homology;
KW Lysosome; Membrane; Reference proteome.
FT CHAIN 1..105
FT /note="BLOC-1-related complex subunit 7"
FT /id="PRO_0000359786"
SQ SEQUENCE 105 AA; 11562 MW; 01FC003564010CEB CRC64;
MATGTPDSQA RFGQSVKGLL TEKVNTCGTD VIALTKQVLK GSRSSELLGQ AARNMVLQED
AILHSEDSLR KMAIITTHLQ YQQEAIQKNV EQSSNLQDQL NHLLK