BORC8_NEMVE
ID BORC8_NEMVE Reviewed; 187 AA.
AC A7SGF0;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=BLOC-1-related complex subunit 8 homolog {ECO:0000305};
GN ORFNames=v1g233178 {ECO:0000312|EMBL:EDO37257.1};
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6;
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- FUNCTION: May participate in the coupling of lysosomes to microtubule
CC plus-end-directed kinesin motor. {ECO:0000250|UniProtKB:Q96FH0}.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q96FH0}.
CC -!- SIMILARITY: Belongs to the BORCS8 family. {ECO:0000305}.
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DR EMBL; DS469651; EDO37257.1; -; Genomic_DNA.
DR RefSeq; XP_001629320.1; XM_001629270.1.
DR AlphaFoldDB; A7SGF0; -.
DR SMR; A7SGF0; -.
DR STRING; 45351.EDO37257; -.
DR EnsemblMetazoa; EDO37257; EDO37257; NEMVEDRAFT_v1g233178.
DR GeneID; 5508752; -.
DR KEGG; nve:5508752; -.
DR eggNOG; KOG4523; Eukaryota.
DR HOGENOM; CLU_1449342_0_0_1; -.
DR InParanoid; A7SGF0; -.
DR OMA; QHETAND; -.
DR OrthoDB; 1473909at2759; -.
DR PhylomeDB; A7SGF0; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0099078; C:BORC complex; IBA:GO_Central.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR019320; BORCS8.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR21146; PTHR21146; 1.
DR Pfam; PF10167; BORCS8; 1.
PE 3: Inferred from homology;
KW Lysosome; Membrane; Reference proteome.
FT CHAIN 1..187
FT /note="BLOC-1-related complex subunit 8 homolog"
FT /id="PRO_0000343674"
FT REGION 165..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 187 AA; 21275 MW; B52A51ED073E46D0 CRC64;
MSGPIGLEVQ HPETEYRLKK VSEKFIESIH LMVNEPSVGL YRIQEHVRRS LPQLVDKKME
LRSCQNQING VCYDLDYSIK TVQSMQHIPH FTIIQECLRS AIASKKNLDA AKLERRSKKV
DEGSGAQSAD AVSEVSIETQ DVEGFICPNC MQVLTSQDEL LEHWQSQHET ANDTRQGYND
DANNDQD