ID   BORC8_TETNG             Reviewed;         118 AA.
AC   Q4S3C1;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=BLOC-1-related complex subunit 8 {ECO:0000305};
GN   Name=borcs8 {ECO:0000250|UniProtKB:Q96FH0};
GN   ORFNames=GSTENG00024711001 {ECO:0000312|EMBL:CAG04861.1};
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX   NCBI_TaxID=99883;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA   Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA   Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA   Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA   Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA   Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA   McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA   Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA   Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA   Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT   early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
CC   -!- FUNCTION: As part of a BORC-like complex may play a role in lysosomes
CC       movement and localization at the cell periphery. Associated with the
CC       cytosolic face of lysosomes, this complex may couple lysosomes to
CC       microtubule plus-end-directed kinesin motor.
CC       {ECO:0000250|UniProtKB:Q96FH0}.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250|UniProtKB:Q96FH0}.
CC   -!- SIMILARITY: Belongs to the BORCS8 family. {ECO:0000305}.
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DR   EMBL; CAAE01014751; CAG04861.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4S3C1; -.
DR   SMR; Q4S3C1; -.
DR   STRING; 99883.ENSTNIP00000016178; -.
DR   Ensembl; ENSTNIT00000016389; ENSTNIP00000016178; ENSTNIG00000013195.
DR   KEGG; tng:GSTEN00024711G001; -.
DR   GeneTree; ENSGT00390000014856; -.
DR   HOGENOM; CLU_151479_0_0_1; -.
DR   InParanoid; Q4S3C1; -.
DR   OMA; CYDVEYA; -.
DR   TreeFam; TF313931; -.
DR   Proteomes; UP000007303; Unassembled WGS sequence.
DR   GO; GO:0099078; C:BORC complex; ISS:UniProtKB.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019320; BORCS8.
DR   PANTHER; PTHR21146; PTHR21146; 1.
DR   Pfam; PF10167; BORCS8; 1.
PE   3: Inferred from homology;
KW   Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..118
FT                   /note="BLOC-1-related complex subunit 8"
FT                   /id="PRO_0000269845"
FT   REGION          98..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   118 AA;  13532 MW;  B6C6C4EA5DDC31BA CRC64;
     MEDQEMHLKV RRVADKFTES MYFLANEPSV ALYRLQEHVR RSLPELVQHK TDMQSWEEQS
     QGAIYTVEYA CSAVKSMTNS SIYFKNIDSL LRQTISMKEQ ISNSQGRSPH VSAPSASS