ID   BORE2_CHICK             Reviewed;         312 AA.
AC   P86345;
DT   10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT   10-AUG-2010, sequence version 1.
DT   03-AUG-2022, entry version 31.
DE   RecName: Full=Borealin-2 {ECO:0000250|UniProtKB:Q4V7H8};
DE   AltName: Full=Cell division cycle-associated protein 9 {ECO:0000250|UniProtKB:Q4V7H8};
DE   AltName: Full=Dasra-A {ECO:0000303|PubMed:15260989};
DE            Short=GgDasraA {ECO:0000303|PubMed:15260989};
GN   Name=CDCA9 {ECO:0000250|UniProtKB:Q4V7H8};
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=White Leghorn Hisex {ECO:0000269|PubMed:12445392};
RC   TISSUE=Embryo {ECO:0000269|PubMed:12445392}, and
RC   Head {ECO:0000269|PubMed:12445392};
RX   PubMed=12445392; DOI=10.1016/s0960-9822(02)01296-4;
RA   Boardman P.E., Sanz-Ezquerro J., Overton I.M., Burt D.W., Bosch E.,
RA   Fong W.T., Tickle C., Brown W.R., Wilson S.A., Hubbard S.J.;
RT   "A comprehensive collection of chicken cDNAs.";
RL   Curr. Biol. 12:1965-1969(2002).
RN   [2] {ECO:0000305}
RP   IDENTIFICATION.
RX   PubMed=15260989; DOI=10.1016/j.cell.2004.06.026;
RA   Sampath S.C., Ohi R., Leismann O., Salic A., Pozniakovski A., Funabiki H.;
RT   "The chromosomal passenger complex is required for chromatin-induced
RT   microtubule stabilization and spindle assembly.";
RL   Cell 118:187-202(2004).
CC   -!- FUNCTION: Component of the chromosomal passenger complex (CPC), a
CC       complex that acts as a key regulator of mitosis. The CPC complex has
CC       essential functions at the centromere in ensuring correct chromosome
CC       alignment and segregation and is required for chromatin-induced
CC       microtubule stabilization and spindle assembly (By similarity).
CC       {ECO:0000250|UniProtKB:Q4V7H8}.
CC   -!- SUBUNIT: Component of the CPC complex. {ECO:0000250|UniProtKB:Q4V7H8}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q4V7H8}.
CC       Chromosome, centromere {ECO:0000250|UniProtKB:Q4V7H8}. Note=Localizes
CC       on chromosome arms and inner centromeres from prophase through
CC       metaphase and then transferring to the spindle midzone and midbody from
CC       anaphase through cytokinesis. {ECO:0000250|UniProtKB:Q4V7H8}.
CC   -!- SIMILARITY: Belongs to the borealin family. {ECO:0000255}.
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DR   EMBL; BU204597; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BU225566; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BU225870; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BU328206; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P86345; -.
DR   SMR; P86345; -.
DR   STRING; 9031.ENSGALP00000033552; -.
DR   PaxDb; P86345; -.
DR   VEuPathDB; HostDB:geneid_415745; -.
DR   eggNOG; ENOG502S23P; Eukaryota.
DR   InParanoid; P86345; -.
DR   OrthoDB; 1338969at2759; -.
DR   PhylomeDB; P86345; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0032133; C:chromosome passenger complex; IBA:GO_Central.
DR   GO; GO:0000775; C:chromosome, centromeric region; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051233; C:spindle midzone; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IBA:GO_Central.
DR   InterPro; IPR018851; Borealin_N.
DR   InterPro; IPR018867; Cell_div_borealin.
DR   Pfam; PF10512; Borealin; 1.
DR   Pfam; PF10444; Nbl1_Borealin_N; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Centromere; Chromosome; Mitosis; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..312
FT                   /note="Borealin-2"
FT                   /id="PRO_0000397222"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   312 AA;  34246 MW;  51BCDED678BBDBAA CRC64;
     MPPRKAPAKR RSTDSGVERD RGALSQEKKD QRIALFLSDF DQQAKESIRE MKKELDLLLQ
     MAEKAFMVEL LKMPTAIRKM KRKDLLNLQE GEEVALAAAA TDCALEDVPS PKVTRTNSKK
     VKVTTIVEYE DAKYTSTKKI PKKVSKSKSL VSLSSGLNSK LHSLSRSVYS STSVNEAVKT
     PASDCSATNF KAMPKVSKSA GLQQAVSRTV PTSERVQGMV LRSKSVPQDK MVPFVNIPLA
     DGQTLCMAGG DLRNIDVQLL NQDTVQHIHN LVVSLNQQTC IPTHSSTLSC EINVPGADSS
     CVFLLRLRNT SD