ID   BOS1_KLULA              Reviewed;         248 AA.
AC   Q6CRX0;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Protein transport protein BOS1;
GN   Name=BOS1; OrderedLocusNames=KLLA0D05775g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: SNARE required for protein transport between the ER and the
CC       Golgi complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC       pass type IV membrane protein {ECO:0000250}. Endoplasmic reticulum
CC       membrane {ECO:0000250}; Single-pass type IV membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BOS1 family. {ECO:0000305}.
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DR   EMBL; CR382124; CAH00415.1; -; Genomic_DNA.
DR   RefSeq; XP_453319.1; XM_453319.1.
DR   AlphaFoldDB; Q6CRX0; -.
DR   SMR; Q6CRX0; -.
DR   STRING; 28985.XP_453319.1; -.
DR   PRIDE; Q6CRX0; -.
DR   EnsemblFungi; CAH00415; CAH00415; KLLA0_D05775g.
DR   GeneID; 2893055; -.
DR   KEGG; kla:KLLA0_D05775g; -.
DR   eggNOG; KOG3251; Eukaryota.
DR   HOGENOM; CLU_078260_1_0_1; -.
DR   InParanoid; Q6CRX0; -.
DR   OMA; FCWLVIH; -.
DR   Proteomes; UP000000598; Chromosome D.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:EnsemblFungi.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031201; C:SNARE complex; IEA:EnsemblFungi.
DR   GO; GO:0005484; F:SNAP receptor activity; IEA:EnsemblFungi.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:EnsemblFungi.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:EnsemblFungi.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:EnsemblFungi.
DR   InterPro; IPR027027; GOSR2/Membrin/Bos1.
DR   PIRSF; PIRSF028865; Membrin-2; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..248
FT                   /note="Protein transport protein BOS1"
FT                   /id="PRO_0000207554"
FT   TOPO_DOM        1..226
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical; Anchor for type IV membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        248
FT                   /note="Vesicular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   248 AA;  28721 MW;  6B54FC8008E2C8FA CRC64;
     MNALYNHAIK QRSLLNKDLG KFEKELVTAP ISLQGAIATT LVSFEKTLHQ YKEQYKQYQI
     NSSDDNDETK LKYETRLQTL TQDYEDAKEK FTELKQKYSE INARDQLFNQ QASMVEETVM
     NKRNINAPPQ TSFGIGALDQ NSERMTINSA AGLPLYEGLR KENSIFERGN AHLDRILQMG
     QESLEDIMEQ NRVLQRLQSQ MTKSLHVLGV SNETIEKINK RLFKDKLIFY IGLLLLILGI
     YFVLKWFG