BOS1_SCHPO
ID BOS1_SCHPO Reviewed; 235 AA.
AC Q9P7G5;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Protein transport protein bos1;
GN Name=bos1; ORFNames=SPAP14E8.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: SNARE required for targeting and fusion of ER-derived
CC transport vesicles with the Golgi complex. {ECO:0000250}.
CC -!- SUBUNIT: Component of a SNARE complex consisting of sed5, bos1, bet1
CC and sec22 or ykt6. Interacts with YIF1 and YIP1 (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type IV membrane protein {ECO:0000250}. Endoplasmic reticulum
CC membrane {ECO:0000250}; Single-pass type IV membrane protein
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BOS1 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB77004.1; -; Genomic_DNA.
DR RefSeq; NP_593539.1; NM_001018973.2.
DR AlphaFoldDB; Q9P7G5; -.
DR SMR; Q9P7G5; -.
DR STRING; 4896.SPAP14E8.03.1; -.
DR iPTMnet; Q9P7G5; -.
DR MaxQB; Q9P7G5; -.
DR PaxDb; Q9P7G5; -.
DR PRIDE; Q9P7G5; -.
DR EnsemblFungi; SPAP14E8.03.1; SPAP14E8.03.1:pep; SPAP14E8.03.
DR GeneID; 2541965; -.
DR KEGG; spo:SPAP14E8.03; -.
DR PomBase; SPAP14E8.03; bos1.
DR VEuPathDB; FungiDB:SPAP14E8.03; -.
DR eggNOG; KOG3251; Eukaryota.
DR HOGENOM; CLU_078260_1_0_1; -.
DR InParanoid; Q9P7G5; -.
DR OMA; FCWLVIH; -.
DR PhylomeDB; Q9P7G5; -.
DR Reactome; R-SPO-204005; COPII-mediated vesicle transport.
DR Reactome; R-SPO-5694530; Cargo concentration in the ER.
DR Reactome; R-SPO-6807878; COPI-mediated anterograde transport.
DR PRO; PR:Q9P7G5; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; ISO:PomBase.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031902; C:late endosome membrane; IBA:GO_Central.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; ISO:PomBase.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISO:PomBase.
DR GO; GO:0006886; P:intracellular protein transport; ISO:PomBase.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR InterPro; IPR027027; GOSR2/Membrin/Bos1.
DR PIRSF; PIRSF028865; Membrin-2; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..235
FT /note="Protein transport protein bos1"
FT /id="PRO_0000207555"
FT TOPO_DOM 1..213
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 235
FT /note="Vesicular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 235 AA; 26855 MW; 559F4F10AD58785C CRC64;
MSNTLYNHCT KLFQSIQRSL DELERGVQDE SNTISLAGIQ GQISASFLSL SRSIDDYDSM
VQRELVPAKK KKATIRIQEF RQKHVQLLEK FDELKAHVRD IAQAKNRKEL LGRRGYVNSL
DSPYGNSTTD AEIVEGPSDL SRQDGLLKEH DFLGRAESQV DEFLERGRMI LGDLVEQGSV
LKATKTKVLN AANTLGITRH TLSLINRRSK QDKIIFYCGA FLVFVLFYLI YRWLR
