ID   T106C_BOVIN             Reviewed;         249 AA.
AC   Q3T144;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Transmembrane protein 106C;
GN   Name=TMEM106C;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}. Membrane
CC       {ECO:0000250|UniProtKB:Q9BVX2}; Lipid-anchor
CC       {ECO:0000250|UniProtKB:Q9BVX2}.
CC   -!- SIMILARITY: Belongs to the TMEM106 family. {ECO:0000305}.
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DR   EMBL; BC102134; AAI02135.1; -; mRNA.
DR   RefSeq; NP_001029633.1; NM_001034461.2.
DR   RefSeq; XP_005206435.1; XM_005206378.3.
DR   RefSeq; XP_005206436.1; XM_005206379.3.
DR   RefSeq; XP_005206437.1; XM_005206380.3.
DR   AlphaFoldDB; Q3T144; -.
DR   STRING; 9913.ENSBTAP00000000578; -.
DR   PaxDb; Q3T144; -.
DR   Ensembl; ENSBTAT00000000578; ENSBTAP00000000578; ENSBTAG00000000454.
DR   GeneID; 514271; -.
DR   KEGG; bta:514271; -.
DR   CTD; 79022; -.
DR   VEuPathDB; HostDB:ENSBTAG00000000454; -.
DR   VGNC; VGNC:35946; TMEM106C.
DR   eggNOG; ENOG502QQ43; Eukaryota.
DR   GeneTree; ENSGT00940000161281; -.
DR   HOGENOM; CLU_089337_0_0_1; -.
DR   InParanoid; Q3T144; -.
DR   OMA; PYVYAFC; -.
DR   OrthoDB; 1175832at2759; -.
DR   TreeFam; TF328907; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000000454; Expressed in caput epididymis and 105 other tissues.
DR   ExpressionAtlas; Q3T144; baseline and differential.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009790; TMEM106.
DR   PANTHER; PTHR28556; PTHR28556; 1.
DR   Pfam; PF07092; DUF1356; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Lipoprotein; Membrane; Myristate;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVX2"
FT   CHAIN           2..249
FT                   /note="Transmembrane protein 106C"
FT                   /id="PRO_0000243899"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BVX2"
SQ   SEQUENCE   249 AA;  27869 MW;  F34479BD79C1BEE5 CRC64;
     MGSRHSTYAH RPFSKRRKAD DTEDSLAERE QQEAIAQFPY VEFTGRDSIT CLTCQGTGYI
     PEQVNELVAL IPHSDQRLRP QRTKQYVLLS ILLCLLASGL VVFFLFPHSV LVDDDGIKVV
     KVTFDEQRSL VILAITATLK IRNSNFYSVA VTSLSSEVQY MNTVVGSYTT TNISLIPPRS
     EHLVNFTAKA EMGGPYSYVY FFCTLPYIGV HNVVVFVRTS VKISYIGHVT QSSLETHHYV
     DCGVNSTAV