T10IP_HUMAN
ID T10IP_HUMAN Reviewed; 556 AA.
AC Q3SY00; Q3SXZ9; Q3SY01; Q96M26;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JUL-2014, sequence version 2.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Testis-specific protein 10-interacting protein;
DE AltName: Full=Tsga10-interacting protein;
GN Name=TSGA10IP;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), AND VARIANT
RP VAL-521.
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q3SY00; Q9ULX6: AKAP8L; NbExp=3; IntAct=EBI-10241197, EBI-357530;
CC Q3SY00; Q9Y2J4: AMOTL2; NbExp=3; IntAct=EBI-10241197, EBI-746752;
CC Q3SY00; Q10567-3: AP1B1; NbExp=3; IntAct=EBI-10241197, EBI-11978055;
CC Q3SY00; O43307: ARHGEF9; NbExp=3; IntAct=EBI-10241197, EBI-3447299;
CC Q3SY00; Q6PI77: BHLHB9; NbExp=3; IntAct=EBI-10241197, EBI-11519926;
CC Q3SY00; Q8TD16-2: BICD2; NbExp=3; IntAct=EBI-10241197, EBI-11975051;
CC Q3SY00; A1A5D9: BICDL2; NbExp=3; IntAct=EBI-10241197, EBI-10171799;
CC Q3SY00; Q96CA5: BIRC7; NbExp=3; IntAct=EBI-10241197, EBI-517623;
CC Q3SY00; Q9NX04: C1orf109; NbExp=3; IntAct=EBI-10241197, EBI-8643161;
CC Q3SY00; Q13137: CALCOCO2; NbExp=3; IntAct=EBI-10241197, EBI-739580;
CC Q3SY00; Q9H257-2: CARD9; NbExp=6; IntAct=EBI-10241197, EBI-11530605;
CC Q3SY00; Q6NZI2: CAVIN1; NbExp=3; IntAct=EBI-10241197, EBI-2559016;
CC Q3SY00; Q8NA61-2: CBY2; NbExp=3; IntAct=EBI-10241197, EBI-11524851;
CC Q3SY00; Q68D86: CCDC102B; NbExp=3; IntAct=EBI-10241197, EBI-10171570;
CC Q3SY00; Q96HB5: CCDC120; NbExp=3; IntAct=EBI-10241197, EBI-744556;
CC Q3SY00; Q86Z20: CCDC125; NbExp=3; IntAct=EBI-10241197, EBI-11977221;
CC Q3SY00; Q8IYE1: CCDC13; NbExp=3; IntAct=EBI-10241197, EBI-10961312;
CC Q3SY00; Q2TAC2: CCDC57; NbExp=3; IntAct=EBI-10241197, EBI-2808286;
CC Q3SY00; Q2TAC2-2: CCDC57; NbExp=3; IntAct=EBI-10241197, EBI-10961624;
CC Q3SY00; A6NC98: CCDC88B; NbExp=3; IntAct=EBI-10241197, EBI-347573;
CC Q3SY00; P55273: CDKN2D; NbExp=3; IntAct=EBI-10241197, EBI-745859;
CC Q3SY00; Q01850: CDR2; NbExp=3; IntAct=EBI-10241197, EBI-1181367;
CC Q3SY00; Q86X02: CDR2L; NbExp=6; IntAct=EBI-10241197, EBI-11063830;
CC Q3SY00; Q96MT8-3: CEP63; NbExp=3; IntAct=EBI-10241197, EBI-11522539;
CC Q3SY00; Q8NHQ1: CEP70; NbExp=7; IntAct=EBI-10241197, EBI-739624;
CC Q3SY00; Q99828: CIB1; NbExp=3; IntAct=EBI-10241197, EBI-372594;
CC Q3SY00; Q8N4Y2-3: CRACR2B; NbExp=3; IntAct=EBI-10241197, EBI-11982645;
CC Q3SY00; P78358: CTAG1B; NbExp=3; IntAct=EBI-10241197, EBI-1188472;
CC Q3SY00; A8MQ03: CYSRT1; NbExp=3; IntAct=EBI-10241197, EBI-3867333;
CC Q3SY00; Q9NPF5: DMAP1; NbExp=3; IntAct=EBI-10241197, EBI-399105;
CC Q3SY00; Q8WWB3: DYDC1; NbExp=3; IntAct=EBI-10241197, EBI-740680;
CC Q3SY00; Q5JVL4: EFHC1; NbExp=3; IntAct=EBI-10241197, EBI-743105;
CC Q3SY00; O94868-3: FCHSD2; NbExp=3; IntAct=EBI-10241197, EBI-11958845;
CC Q3SY00; Q13643: FHL3; NbExp=5; IntAct=EBI-10241197, EBI-741101;
CC Q3SY00; O43559: FRS3; NbExp=3; IntAct=EBI-10241197, EBI-725515;
CC Q3SY00; A1L4K1: FSD2; NbExp=3; IntAct=EBI-10241197, EBI-5661036;
CC Q3SY00; O95995: GAS8; NbExp=3; IntAct=EBI-10241197, EBI-1052570;
CC Q3SY00; Q08379: GOLGA2; NbExp=3; IntAct=EBI-10241197, EBI-618309;
CC Q3SY00; Q9NYA3: GOLGA6A; NbExp=3; IntAct=EBI-10241197, EBI-11163335;
CC Q3SY00; A6NEM1: GOLGA6L9; NbExp=3; IntAct=EBI-10241197, EBI-5916454;
CC Q3SY00; Q4V328: GRIPAP1; NbExp=3; IntAct=EBI-10241197, EBI-717919;
CC Q3SY00; Q6NT76: HMBOX1; NbExp=3; IntAct=EBI-10241197, EBI-2549423;
CC Q3SY00; Q96ED9-2: HOOK2; NbExp=3; IntAct=EBI-10241197, EBI-10961706;
CC Q3SY00; O75031: HSF2BP; NbExp=3; IntAct=EBI-10241197, EBI-7116203;
CC Q3SY00; Q9UKT9: IKZF3; NbExp=3; IntAct=EBI-10241197, EBI-747204;
CC Q3SY00; Q96N16: JAKMIP1; NbExp=3; IntAct=EBI-10241197, EBI-2680803;
CC Q3SY00; Q63ZY3: KANK2; NbExp=3; IntAct=EBI-10241197, EBI-2556193;
CC Q3SY00; O75525: KHDRBS3; NbExp=3; IntAct=EBI-10241197, EBI-722504;
CC Q3SY00; Q9BVG8-5: KIFC3; NbExp=3; IntAct=EBI-10241197, EBI-14069005;
CC Q3SY00; Q2M2I5: KRT24; NbExp=3; IntAct=EBI-10241197, EBI-2952736;
CC Q3SY00; O76013-2: KRT36; NbExp=3; IntAct=EBI-10241197, EBI-11958506;
CC Q3SY00; Q6A162: KRT40; NbExp=3; IntAct=EBI-10241197, EBI-10171697;
CC Q3SY00; O43790: KRT86; NbExp=3; IntAct=EBI-10241197, EBI-9996498;
CC Q3SY00; P59991: KRTAP12-2; NbExp=3; IntAct=EBI-10241197, EBI-10176379;
CC Q3SY00; Q3LI66: KRTAP6-2; NbExp=3; IntAct=EBI-10241197, EBI-11962084;
CC Q3SY00; O95447: LCA5L; NbExp=3; IntAct=EBI-10241197, EBI-8473670;
CC Q3SY00; O95751: LDOC1; NbExp=3; IntAct=EBI-10241197, EBI-740738;
CC Q3SY00; Q05469: LIPE; NbExp=3; IntAct=EBI-10241197, EBI-721601;
CC Q3SY00; Q03252: LMNB2; NbExp=3; IntAct=EBI-10241197, EBI-2830427;
CC Q3SY00; P25791-3: LMO2; NbExp=3; IntAct=EBI-10241197, EBI-11959475;
CC Q3SY00; Q9Y250: LZTS1; NbExp=3; IntAct=EBI-10241197, EBI-1216080;
CC Q3SY00; Q9Y5V3: MAGED1; NbExp=3; IntAct=EBI-10241197, EBI-716006;
CC Q3SY00; Q8WWY6: MBD3L1; NbExp=3; IntAct=EBI-10241197, EBI-12516603;
CC Q3SY00; Q99750: MDFI; NbExp=3; IntAct=EBI-10241197, EBI-724076;
CC Q3SY00; Q99687-3: MEIS3; NbExp=3; IntAct=EBI-10241197, EBI-18582591;
CC Q3SY00; Q6FHY5: MEOX2; NbExp=3; IntAct=EBI-10241197, EBI-16439278;
CC Q3SY00; Q8TD10: MIPOL1; NbExp=3; IntAct=EBI-10241197, EBI-2548751;
CC Q3SY00; Q9NYP9: MIS18A; NbExp=3; IntAct=EBI-10241197, EBI-1104552;
CC Q3SY00; Q13064: MKRN3; NbExp=3; IntAct=EBI-10241197, EBI-2340269;
CC Q3SY00; Q4VC12: MSS51; NbExp=3; IntAct=EBI-10241197, EBI-11599933;
CC Q3SY00; Q5JR59: MTUS2; NbExp=4; IntAct=EBI-10241197, EBI-742948;
CC Q3SY00; Q5JR59-3: MTUS2; NbExp=4; IntAct=EBI-10241197, EBI-11522433;
CC Q3SY00; Q15742: NAB2; NbExp=3; IntAct=EBI-10241197, EBI-8641936;
CC Q3SY00; Q9HBI0: PARVG; NbExp=3; IntAct=EBI-10241197, EBI-3921217;
CC Q3SY00; Q9NR12: PDLIM7; NbExp=3; IntAct=EBI-10241197, EBI-350517;
CC Q3SY00; Q9NRD5: PICK1; NbExp=3; IntAct=EBI-10241197, EBI-79165;
CC Q3SY00; Q9NQX0: PRDM6; NbExp=3; IntAct=EBI-10241197, EBI-11320284;
CC Q3SY00; P31321: PRKAR1B; NbExp=3; IntAct=EBI-10241197, EBI-2805516;
CC Q3SY00; O43586: PSTPIP1; NbExp=3; IntAct=EBI-10241197, EBI-1050964;
CC Q3SY00; Q0VAM2-3: RASGEF1B; NbExp=3; IntAct=EBI-10241197, EBI-12013954;
CC Q3SY00; Q9BQ04: RBM4B; NbExp=3; IntAct=EBI-10241197, EBI-715531;
CC Q3SY00; Q93062-3: RBPMS; NbExp=3; IntAct=EBI-10241197, EBI-740343;
CC Q3SY00; Q9HAT0: ROPN1; NbExp=3; IntAct=EBI-10241197, EBI-1378139;
CC Q3SY00; Q92753-1: RORB; NbExp=3; IntAct=EBI-10241197, EBI-18560266;
CC Q3SY00; Q59EK9-3: RUNDC3A; NbExp=3; IntAct=EBI-10241197, EBI-11957366;
CC Q3SY00; O60504: SORBS3; NbExp=3; IntAct=EBI-10241197, EBI-741237;
CC Q3SY00; Q9NZD8: SPG21; NbExp=3; IntAct=EBI-10241197, EBI-742688;
CC Q3SY00; Q9Y2D8: SSX2IP; NbExp=3; IntAct=EBI-10241197, EBI-2212028;
CC Q3SY00; O75558: STX11; NbExp=3; IntAct=EBI-10241197, EBI-714135;
CC Q3SY00; Q16623: STX1A; NbExp=3; IntAct=EBI-10241197, EBI-712466;
CC Q3SY00; Q86TI0: TBC1D1; NbExp=3; IntAct=EBI-10241197, EBI-1644036;
CC Q3SY00; Q969V4: TEKT1; NbExp=3; IntAct=EBI-10241197, EBI-10180409;
CC Q3SY00; Q9UBB9: TFIP11; NbExp=3; IntAct=EBI-10241197, EBI-1105213;
CC Q3SY00; Q08117-2: TLE5; NbExp=3; IntAct=EBI-10241197, EBI-11741437;
CC Q3SY00; Q12933: TRAF2; NbExp=3; IntAct=EBI-10241197, EBI-355744;
CC Q3SY00; Q9BUZ4: TRAF4; NbExp=3; IntAct=EBI-10241197, EBI-3650647;
CC Q3SY00; P14373: TRIM27; NbExp=3; IntAct=EBI-10241197, EBI-719493;
CC Q3SY00; Q9C035-3: TRIM5; NbExp=3; IntAct=EBI-10241197, EBI-12840050;
CC Q3SY00; Q86XT4: TRIM50; NbExp=3; IntAct=EBI-10241197, EBI-9867283;
CC Q3SY00; Q15654: TRIP6; NbExp=3; IntAct=EBI-10241197, EBI-742327;
CC Q3SY00; Q86WV8: TSC1; NbExp=3; IntAct=EBI-10241197, EBI-12806590;
CC Q3SY00; Q5W5X9-3: TTC23; NbExp=3; IntAct=EBI-10241197, EBI-9090990;
CC Q3SY00; Q6PF05: TTC23L; NbExp=3; IntAct=EBI-10241197, EBI-8656864;
CC Q3SY00; Q8TAS1-2: UHMK1; NbExp=3; IntAct=EBI-10241197, EBI-12157345;
CC Q3SY00; Q9NZC7-5: WWOX; NbExp=5; IntAct=EBI-10241197, EBI-12040603;
CC Q3SY00; P07947: YES1; NbExp=3; IntAct=EBI-10241197, EBI-515331;
CC Q3SY00; Q9UGI0: ZRANB1; NbExp=3; IntAct=EBI-10241197, EBI-527853;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q3SY00-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3SY00-2; Sequence=VSP_033196, VSP_033197;
CC -!- CAUTION: It is uncertain whether Met-1 or Met-7 is the initiator.
CC {ECO:0000305}.
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DR EMBL; AK057442; BAB71488.1; -; mRNA.
DR EMBL; AP006287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC104022; AAI04023.1; -; mRNA.
DR EMBL; BC104023; AAI04024.1; -; mRNA.
DR CCDS; CCDS66138.1; -. [Q3SY00-1]
DR RefSeq; NP_689975.2; NM_152762.2. [Q3SY00-1]
DR AlphaFoldDB; Q3SY00; -.
DR SMR; Q3SY00; -.
DR BioGRID; 129021; 141.
DR IntAct; Q3SY00; 114.
DR STRING; 9606.ENSP00000484252; -.
DR iPTMnet; Q3SY00; -.
DR PhosphoSitePlus; Q3SY00; -.
DR BioMuta; TSGA10IP; -.
DR DMDM; 121942943; -.
DR MassIVE; Q3SY00; -.
DR PeptideAtlas; Q3SY00; -.
DR PRIDE; Q3SY00; -.
DR Antibodypedia; 72461; 99 antibodies from 16 providers.
DR DNASU; 254187; -.
DR Ensembl; ENST00000532620.5; ENSP00000484252.1; ENSG00000175513.9. [Q3SY00-1]
DR Ensembl; ENST00000608857.2; ENSP00000477317.2; ENSG00000175513.9. [Q3SY00-2]
DR GeneID; 254187; -.
DR KEGG; hsa:254187; -.
DR MANE-Select; ENST00000532620.6; ENSP00000484252.1; NM_152762.3; NP_689975.2.
DR UCSC; uc009yqw.2; human. [Q3SY00-1]
DR CTD; 254187; -.
DR DisGeNET; 254187; -.
DR GeneCards; TSGA10IP; -.
DR HGNC; HGNC:26555; TSGA10IP.
DR HPA; ENSG00000175513; Tissue enriched (testis).
DR neXtProt; NX_Q3SY00; -.
DR OpenTargets; ENSG00000175513; -.
DR PharmGKB; PA134983361; -.
DR VEuPathDB; HostDB:ENSG00000175513; -.
DR eggNOG; ENOG502S4NS; Eukaryota.
DR GeneTree; ENSGT00390000008351; -.
DR HOGENOM; CLU_037959_0_0_1; -.
DR InParanoid; Q3SY00; -.
DR OMA; DCGPQKQ; -.
DR OrthoDB; 1171000at2759; -.
DR PathwayCommons; Q3SY00; -.
DR SignaLink; Q3SY00; -.
DR BioGRID-ORCS; 254187; 9 hits in 629 CRISPR screens.
DR ChiTaRS; TSGA10IP; human.
DR GenomeRNAi; 254187; -.
DR Pharos; Q3SY00; Tdark.
DR PRO; PR:Q3SY00; -.
DR Proteomes; UP000005640; Chromosome 11.
DR RNAct; Q3SY00; protein.
DR Bgee; ENSG00000175513; Expressed in left testis and 53 other tissues.
DR ExpressionAtlas; Q3SY00; baseline and differential.
DR Genevisible; Q3SY00; HS.
DR GO; GO:0032391; C:photoreceptor connecting cilium; IBA:GO_Central.
DR GO; GO:0044782; P:cilium organization; IBA:GO_Central.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..556
FT /note="Testis-specific protein 10-interacting protein"
FT /id="PRO_0000331421"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 379..464
FT /evidence="ECO:0000255"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 336..404
FT /note="PQKLPWKTLRAAFQASKRNGKAYASGYDETFVSANLPNRTFHKRQEATRSLL
FT QAWERQRQEERQQAELR -> SHQEPAAGLGAAAAGGAAAGRAAAGPDTACTAAGGPLP
FT GSLRTQREPGPWGGPAQAGGAEAPGATALC (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_033196"
FT VAR_SEQ 405..556
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_033197"
FT VARIANT 210
FT /note="A -> V (in dbSNP:rs565921)"
FT /id="VAR_042855"
FT VARIANT 237
FT /note="R -> S (in dbSNP:rs7927388)"
FT /id="VAR_042856"
FT VARIANT 292
FT /note="S -> N (in dbSNP:rs7927826)"
FT /id="VAR_042857"
FT VARIANT 305
FT /note="R -> P (in dbSNP:rs7927841)"
FT /id="VAR_042858"
FT VARIANT 521
FT /note="M -> V (in dbSNP:rs491973)"
FT /evidence="ECO:0000269|PubMed:15489334"
FT /id="VAR_042859"
FT CONFLICT 67
FT /note="S -> P (in Ref. 1; BAB71488)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 556 AA; 62381 MW; A676754C093FDA61 CRC64;
MGQDTDMLNT YQQLVRTPSV RPGQDVRLQA PGTRTGLLKL LSTVSQDKQG CLGSGDGVPN
QDLQQRSQSS RQTAKKDRKP RGQSKKGQGS EESEDHFPLL PRKPSFPFQW AWESIATDVR
AVLQPSSPTP GHQALPMPSS FSQRQSRRKS TANLPEAHGC CWKTEAQNLK ARQQLGAWGG
VSIPTGKGEL GSEPPSGLQL PGRRPGSGSA SDKQVQLQSL GAEEAERGLS SGVLPQRPRR
GSISEEEQFS EATEEAEEGE HRTPCRRRAG CQRKGQISGE EASDEGEVQG QSQGSSPSFN
NLRRRQWRKT RAKELQGPWD LEKLHRQLQR DLDCGPQKLP WKTLRAAFQA SKRNGKAYAS
GYDETFVSAN LPNRTFHKRQ EATRSLLQAW ERQRQEERQQ AELRRARTQH VQRQVAHCLA
AYAPRGSRGP GAAQRKLEEL RRQERQRFAE YQAELQGIQH RVQARPFLFQ QAMQANARLT
VTRRFSQVLS ALGLDEEQLL SEAGKVDREG TPRKPRSHRS MGVRMEHSPQ RPPRTEPTGS
QPDRHYNPSL DPECSP
