T10IP_RAT
ID T10IP_RAT Reviewed; 536 AA.
AC Q66MI6; Q4QRC4;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 2.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Testis-specific protein 10-interacting protein;
DE AltName: Full=Tsga10-interacting protein;
GN Name=Tsga10ip;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RC STRAIN=Sprague-Dawley; TISSUE=Testis;
RA Behnam B., Manistre S., Hoorn F.V., Wolfe J.;
RT "Rattus norvegicus homolog of the gene encoding a (fibrous sheath) protein
RT (TSGA10IP) that interacts with TSGA10.";
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q66MI6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q66MI6-2; Sequence=VSP_033198;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAU04556.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AY690667; AAU04556.1; ALT_FRAME; mRNA.
DR EMBL; BC097254; AAH97254.1; -; mRNA.
DR RefSeq; NP_001004278.2; NM_001004278.3. [Q66MI6-2]
DR RefSeq; NP_001257665.1; NM_001270736.1.
DR RefSeq; NP_001257666.1; NM_001270737.1. [Q66MI6-1]
DR AlphaFoldDB; Q66MI6; -.
DR SMR; Q66MI6; -.
DR PhosphoSitePlus; Q66MI6; -.
DR GeneID; 361707; -.
DR KEGG; rno:361707; -.
DR UCSC; RGD:1302964; rat. [Q66MI6-1]
DR CTD; 254187; -.
DR RGD; 1302964; Tsga10ip.
DR eggNOG; ENOG502S4NS; Eukaryota.
DR InParanoid; Q66MI6; -.
DR OrthoDB; 1171000at2759; -.
DR PhylomeDB; Q66MI6; -.
DR TreeFam; TF321199; -.
DR PRO; PR:Q66MI6; -.
DR Proteomes; UP000002494; Unplaced.
DR GO; GO:0032391; C:photoreceptor connecting cilium; IBA:GO_Central.
DR GO; GO:0044782; P:cilium organization; IBA:GO_Central.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..536
FT /note="Testis-specific protein 10-interacting protein"
FT /id="PRO_0000331423"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 375..451
FT /evidence="ECO:0000255"
FT COMPBIAS 30..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 369
FT /note="A -> ATRTWALRDTYFFPQSLTSGPHAPPCYLGLPRAPDPHGHPPFL (in
FT isoform 2)"
FT /evidence="ECO:0000303|Ref.1"
FT /id="VSP_033198"
SQ SEQUENCE 536 AA; 59788 MW; 21EA521F6F8A7FF1 CRC64;
MLNTDQLLVR AISERPRKST EPLVPGTPTG LFSLLSNISP EEQGRLGSGD SLQSQSCQQQ
RSYSAGQTTK KERKPRRRNK KGRGSAEAED LFSSPRKPSF PFQWAWESFI IDGQALLQSG
SSVAVGHRSL LFPPAAPQCK TRHKSVANLS EDLRACHKSE VQNLGRRYQP GAWANLSLPL
GKAESQGLER PTFWSTGKGS GSECEDVSEV EGQNADEAEK SLSTGELPQL PGQGLTLEEE
LISEVMEEEE HNRRKGSSVN KGRNSGEKGS EEGELQSHNQ GSSSNSNSLR KSPKGTSGAK
EFKGPWDLER LHRQLQEELE SGPQKQTWKA LRAAVQASAR NRKTPVTGEE ESFLTANFPN
RTFHKRQEAT RNLLQAWEQQ QLKEKQQAEM RRAREQQVQQ QVARCLAAYT PGGNRGTLGP
QRKLEELRRK ERQRFAEYQA ELQGIQHRVQ ARPFLFQQAM QTNARLTANR RFSQVLSALG
VDEEQLLAEA GNAEGIPRKH RSYRSFGVEM ESSPQSPPKT EPTSSQPGRH PSPTLD