T111_SCHPO
ID T111_SCHPO Reviewed; 979 AA.
AC Q09813;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Putative transcription initiation factor TFIID 111 kDa subunit;
DE AltName: Full=TAFII-111;
DE AltName: Full=TBP-associated factor 111 kDa;
GN ORFNames=SPAC2G11.14;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-244, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- FUNCTION: TAFs are components of the transcription factor IID (TFIID)
CC complex that are essential for mediating regulation of RNA polymerase
CC transcription. {ECO:0000250}.
CC -!- SUBUNIT: TFIID is composed of TATA binding protein (TBP) and a number
CC of TBP-associated factors (TAFs).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; CU329670; CAA91179.1; -; Genomic_DNA.
DR PIR; T38580; S62469.
DR RefSeq; NP_593094.1; NM_001018492.2.
DR AlphaFoldDB; Q09813; -.
DR SMR; Q09813; -.
DR BioGRID; 278339; 7.
DR DIP; DIP-36781N; -.
DR IntAct; Q09813; 4.
DR STRING; 4896.SPAC2G11.14.1; -.
DR iPTMnet; Q09813; -.
DR MaxQB; Q09813; -.
DR PaxDb; Q09813; -.
DR PRIDE; Q09813; -.
DR EnsemblFungi; SPAC2G11.14.1; SPAC2G11.14.1:pep; SPAC2G11.14.
DR GeneID; 2541848; -.
DR KEGG; spo:SPAC2G11.14; -.
DR PomBase; SPAC2G11.14; -.
DR VEuPathDB; FungiDB:SPAC2G11.14; -.
DR eggNOG; KOG0008; Eukaryota.
DR HOGENOM; CLU_000572_0_0_1; -.
DR InParanoid; Q09813; -.
DR OMA; MLSNFGM; -.
DR PhylomeDB; Q09813; -.
DR Reactome; R-SPO-674695; RNA Polymerase II Pre-transcription Events.
DR Reactome; R-SPO-73776; RNA Polymerase II Promoter Escape.
DR Reactome; R-SPO-73779; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening.
DR Reactome; R-SPO-75953; RNA Polymerase II Transcription Initiation.
DR Reactome; R-SPO-76042; RNA Polymerase II Transcription Initiation And Promoter Clearance.
DR PRO; PR:Q09813; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005669; C:transcription factor TFIID complex; IDA:PomBase.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; ISO:PomBase.
DR GO; GO:0001091; F:RNA polymerase II general transcription initiation factor binding; IEA:InterPro.
DR GO; GO:0017025; F:TBP-class protein binding; IBA:GO_Central.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR InterPro; IPR040240; TAF1.
DR InterPro; IPR022591; TAF1_HAT_dom.
DR InterPro; IPR041670; Znf-CCHC_6.
DR PANTHER; PTHR13900; PTHR13900; 2.
DR Pfam; PF12157; DUF3591; 1.
DR Pfam; PF15288; zf-CCHC_6; 1.
PE 1: Evidence at protein level;
KW Nucleus; Phosphoprotein; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..979
FT /note="Putative transcription initiation factor TFIID 111
FT kDa subunit"
FT /id="PRO_0000072397"
FT MOD_RES 244
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 979 AA; 111014 MW; 37873DCC23884701 CRC64;
MSFDGLIVEN ENTKSGYNDG NDLTDLFKQN GTDMSVINSL LGDTNNPGMN ESPKILDSSF
ENSNPQDGPN YEDFDFMGSI HKEFGNNINE MDDMEDVSDD NLPEEEQAVN YTGDKDDEDF
GKLLAKEMGE EAAGQVLSGV GFSIPSGLVP PSEPSKTVSS TTEELQNEAQ IRESIVKTFF
PTFERGVLLN FSELFKPKPV KLAPPKKKTP KVCVPGRLTL EVDTDYAIIF NSKKSLPLKR
NVVSPISTHT KKRRRTANTS QRNDGLDLNT VFTTNDWEKN IIYDESDVNK TNQSSFFIDK
SLVDIDFAFD ENIFDGDTGT SKVVLNLNDP KLLLQPQLPK KEDSQRSFAD THQRNSLAWK
FNISNDPAYE MLKQNHQSKV RNTLSQLAIE HAAFAEKLTF PYYKTRLSKR AVRSYHRPTM
SFKPNAAIVF SPLIVRKRSK DKHKSERELI PTTKEITMGD TTHAILVEFS EEHPAVLSNA
GMASRIVNYY RKKNEQDESR PKLEVGESHV LDVQDRSPFW NFGSVEPGEI TPTLYNKMIR
APLFKHEVPP TDFILIRNSS SYGSKYYLKN INHMFVSGQT FPVTDVPGPH SRKVTTASKN
RLKMLVFRLI RRSPNGGLFI RQLSKHFSDQ NEMQIRQRLK EFMEYKKKGD GPGYWKLKSN
EVVPDEAGTR SMVSPETVCL LESMQVGVRQ LEDAGYGKTM DEINDDEDEE QPAEQLLAPW
ITTRNFINAT QGKAMLTLFG EGDPTGIGEG YSFIRTSMKG GFKPAGETAD DKPEPQTKNA
HAYNVAKQQR AYEEEINRIW NAQKRGLSIN NLEELAKKYG INSIHDDYVE SNEETTREET
PSSDKVLRIV RLYRDKNGNL ERKQETIHDP IVIHAYLKKR REIDEQSTAL DAVVPTGDEA
IDRRNRRRLE QELAKSQKNW ERRRARHAAK EGINLNGEGR KPTTRKCSNC GQVGHMKTNK
ICPLFGRPEG GLATMLDKN
