T112B_ARATH
ID T112B_ARATH Reviewed; 124 AA.
AC Q9C9R3; Q7Y226;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Multifunctional methyltransferase subunit TRM112 homolog B {ECO:0000305};
DE AltName: Full=Multifunctional methyltransferase subunit TRM112-like protein At1g78190 {ECO:0000305};
DE AltName: Full=Protein SMALL ORGAN 2-LIKE {ECO:0000303|PubMed:19929876};
DE AltName: Full=tRNA methyltransferase 112 homolog B {ECO:0000305};
DE Short=AtTRM112b {ECO:0000303|PubMed:21653555};
GN Name=TRM112B {ECO:0000303|PubMed:21653555};
GN Synonyms=SMO2L {ECO:0000303|PubMed:19929876};
GN OrderedLocusNames=At1g78190 {ECO:0000312|Araport:AT1G78190};
GN ORFNames=T11I11.13 {ECO:0000312|EMBL:AAG52099.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 8-124.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=19929876; DOI=10.1111/j.1365-313x.2009.04085.x;
RA Hu Z., Qin Z., Wang M., Xu C., Feng G., Liu J., Meng Z., Hu Y.;
RT "The Arabidopsis SMO2, a homologue of yeast TRM112, modulates progression
RT of cell division during organ growth.";
RL Plant J. 61:600-610(2010).
RN [5]
RP FUNCTION, AND INTERACTION WITH TRM9.
RX PubMed=21653555; DOI=10.1093/nar/gkr406;
RA Leihne V., Kirpekar F., Vaagboe C.B., van den Born E., Krokan H.E.,
RA Grini P.E., Meza T.J., Falnes P.O.;
RT "Roles of Trm9- and ALKBH8-like proteins in the formation of modified
RT wobble uridines in Arabidopsis tRNA.";
RL Nucleic Acids Res. 39:7688-7701(2011).
CC -!- FUNCTION: Acts as an activator of both rRNA/tRNA and protein
CC methyltransferases (By similarity). Required for TRM9 tRNA
CC methyltransferase activity (PubMed:21653555).
CC {ECO:0000250|UniProtKB:P53738, ECO:0000269|PubMed:21653555}.
CC -!- SUBUNIT: Interacts with TRM9. {ECO:0000269|PubMed:21653555}.
CC -!- TISSUE SPECIFICITY: Expressed in anthers.
CC {ECO:0000269|PubMed:19929876}.
CC -!- SIMILARITY: Belongs to the TRM112 family. {ECO:0000305}.
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DR EMBL; AC012680; AAG52099.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36079.1; -; Genomic_DNA.
DR EMBL; BT008329; AAP37688.1; -; mRNA.
DR PIR; C96811; C96811.
DR RefSeq; NP_177943.1; NM_106469.1.
DR AlphaFoldDB; Q9C9R3; -.
DR SMR; Q9C9R3; -.
DR STRING; 3702.AT1G78190.1; -.
DR PaxDb; Q9C9R3; -.
DR PRIDE; Q9C9R3; -.
DR ProteomicsDB; 234110; -.
DR EnsemblPlants; AT1G78190.1; AT1G78190.1; AT1G78190.
DR GeneID; 844155; -.
DR Gramene; AT1G78190.1; AT1G78190.1; AT1G78190.
DR KEGG; ath:AT1G78190; -.
DR Araport; AT1G78190; -.
DR TAIR; locus:2194724; AT1G78190.
DR eggNOG; KOG1088; Eukaryota.
DR HOGENOM; CLU_086140_2_0_1; -.
DR InParanoid; Q9C9R3; -.
DR OMA; MCNKKGV; -.
DR OrthoDB; 1465773at2759; -.
DR PhylomeDB; Q9C9R3; -.
DR PRO; PR:Q9C9R3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C9R3; baseline and differential.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0018364; P:peptidyl-glutamine methylation; IBA:GO_Central.
DR GO; GO:0070476; P:rRNA (guanine-N7)-methylation; IBA:GO_Central.
DR GO; GO:0030488; P:tRNA methylation; IBA:GO_Central.
DR InterPro; IPR039127; Trm112.
DR InterPro; IPR005651; Trm112-like.
DR PANTHER; PTHR12773; PTHR12773; 1.
DR Pfam; PF03966; Trm112p; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..124
FT /note="Multifunctional methyltransferase subunit TRM112
FT homolog B"
FT /id="PRO_0000215802"
FT DOMAIN 2..120
FT /note="TRM112"
SQ SEQUENCE 124 AA; 14262 MW; 7341C81DDEE8B4A8 CRC64;
MRLIVHNMLS CNIKGVVNKF PLRIEAEKVT VKEVDFNPDF LRYMFAKIDW KALVDGARSM
EYTELPDNAP DTTTLESDET FLRKFHHALL ELHLEEGSLV CPETGRKFSV SKGIPNMLLH
EDEV
