ID   T144A_DICDI             Reviewed;         369 AA.
AC   Q55FV8;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Transmembrane protein 144 homolog A;
DE   AltName: Full=Transmembrane protein 144 homolog 1;
GN   Name=tmem144A; ORFNames=DDB_G0267928;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM144 family. {ECO:0000305}.
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DR   EMBL; AAFI02000003; EAL73417.1; -; Genomic_DNA.
DR   RefSeq; XP_647425.1; XM_642333.1.
DR   AlphaFoldDB; Q55FV8; -.
DR   STRING; 44689.DDB0304987; -.
DR   PaxDb; Q55FV8; -.
DR   EnsemblProtists; EAL73417; EAL73417; DDB_G0267928.
DR   GeneID; 8616232; -.
DR   KEGG; ddi:DDB_G0267928; -.
DR   dictyBase; DDB_G0267928; tmem144B.
DR   eggNOG; ENOG502QR0F; Eukaryota.
DR   HOGENOM; CLU_031844_1_0_1; -.
DR   InParanoid; Q55FV8; -.
DR   OMA; WNTSNCL; -.
DR   PhylomeDB; Q55FV8; -.
DR   PRO; PR:Q55FV8; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   InterPro; IPR012435; TMEM144.
DR   PANTHER; PTHR16119; PTHR16119; 1.
DR   Pfam; PF07857; TMEM144; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..369
FT                   /note="Transmembrane protein 144 homolog A"
FT                   /id="PRO_0000328445"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   369 AA;  40639 MW;  E31D0EE0348A16DF CRC64;
     MVNPMVIGYI GSAAAIIGFG SNYVPVKKYP VGNGLSYAFI LSIGGLCVAF IAMMIHGTFV
     FSPIGILGGS LWAMANLLII PIIKLVGLGL GVLLWSSIGI VVGFFSGKFG WLGLEKQIVT
     HDWMNWLGFV GIVISIFCFF FIKPSLEDDN NNKNVVDRFK NKKGGYIDPM DNEEFPILRG
     SVNSDGPIKF NKYNNNNNNG DELETSTETI FDKIPTKFKK VAGISMSIIC GVLLGVNMIP
     MQLWKQNHQE ASPFDIIFSQ FAGVFLFNAF TFMFYAMIKK SPQIYPKTVF PSFISGVMWG
     IANCGLMIST QNLGYTVGYP ISCSGPMIIS SLWSVFYFHE IKGTKNLLIL CGSFLFLISG
     IILLAFSSF