ID   T144B_DICDI             Reviewed;         358 AA.
AC   Q54V96;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Transmembrane protein 144 homolog B;
DE   AltName: Full=Transmembrane protein 144 homolog 2;
GN   Name=tmem144B; ORFNames=DDB_G0280505;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM144 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000036; EAL67232.1; -; Genomic_DNA.
DR   RefSeq; XP_641212.1; XM_636120.1.
DR   AlphaFoldDB; Q54V96; -.
DR   STRING; 44689.DDB0304988; -.
DR   TCDB; 2.A.7.8.2; the drug/metabolite transporter (dmt) superfamily.
DR   PaxDb; Q54V96; -.
DR   EnsemblProtists; EAL67232; EAL67232; DDB_G0280505.
DR   GeneID; 8622593; -.
DR   KEGG; ddi:DDB_G0280505; -.
DR   dictyBase; DDB_G0280505; tmem144A.
DR   eggNOG; ENOG502QR0F; Eukaryota.
DR   HOGENOM; CLU_031844_1_0_1; -.
DR   InParanoid; Q54V96; -.
DR   OMA; GALWCTG; -.
DR   PhylomeDB; Q54V96; -.
DR   PRO; PR:Q54V96; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   InterPro; IPR012435; TMEM144.
DR   PANTHER; PTHR16119; PTHR16119; 1.
DR   Pfam; PF07857; TMEM144; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..358
FT                   /note="Transmembrane protein 144 homolog B"
FT                   /id="PRO_0000328446"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        307..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        337..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   358 AA;  39253 MW;  BC10196DC6E2C924 CRC64;
     MVNPQVIGYI GAAVASLFFG SNYVPVKNYP TGNGLAFTWV MSVGTLVVAY CAMFISKDYI
     FDPWGLLGGT LWSIGNFCVI PIVKTIGIGL GLLLWCCSSI ITGYFTGKFG WFGIDKQKVS
     HPALNWIGFA CIVAAVIFFF FIEPTIEEKD EHSYSSIVDD SEIGNNGIDN NGYNSINNNN
     NNGNNKRRSG AFNKQPKKSI FERMPPPYNT ILGIVLSVFS GIMYGVNMVP MQLWKQSNVD
     ASPLSFVFCH FSGIFLANTA VFIVYSIIVR PPQIFPQTIF PSFFSGLLWG IANVGLMVAT
     QNLGYTIGFP MGSGGPMIVS SLWSVFYFRE IQGVKNLLIL LISFIFLGAG ITILALSH