BP26_BRUME
ID BP26_BRUME Reviewed; 250 AA.
AC P0A3U8; Q57099;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=26 kDa periplasmic immunogenic protein;
DE AltName: Full=28 kDa cytosoluble protein;
DE AltName: Full=28 kDa outer membrane protein;
DE AltName: Full=CP28;
DE Flags: Precursor;
GN Name=bp26; Synonyms=omp28; OrderedLocusNames=BMEI0536;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=8698471; DOI=10.1128/iai.64.7.2490-2499.1996;
RA Lindler L.E., Hadfield T.L., Tall B.D., Snellings N.J., Rubin F.A.,
RA van de Verg L.L., Hoover D., Warren R.L.;
RT "Cloning of a Brucella melitensis group 3 antigen gene encoding Omp28, a
RT protein recognized by the humoral immune response during human
RT brucellosis.";
RL Infect. Immun. 64:2490-2499(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=8764475; DOI=10.1016/0378-1097(96)00169-3;
RA Cloeckaert A., Debbarh H.S., Vizcaino N., Saman E., Dubray G.,
RA Zygmunt M.S.;
RT "Cloning, nucleotide sequence, and expression of the Brucella melitensis
RT bp26 gene coding for a protein immunogenic in infected sheep.";
RL FEMS Microbiol. Lett. 140:139-144(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC -!- SUBCELLULAR LOCATION: Periplasm.
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DR EMBL; U30815; AAB17713.1; -; Genomic_DNA.
DR EMBL; U45996; AAB38523.1; -; Genomic_DNA.
DR EMBL; AE008917; AAL51717.1; -; Genomic_DNA.
DR PIR; AB3319; AB3319.
DR RefSeq; WP_002964581.1; NZ_GG703780.1.
DR AlphaFoldDB; P0A3U8; -.
DR SMR; P0A3U8; -.
DR STRING; 224914.BMEI0536; -.
DR EnsemblBacteria; AAL51717; AAL51717; BMEI0536.
DR GeneID; 45124811; -.
DR GeneID; 55591123; -.
DR KEGG; bme:BMEI0536; -.
DR PATRIC; fig|224914.52.peg.934; -.
DR eggNOG; COG2968; Bacteria.
DR OMA; LPNGPHI; -.
DR PRO; PR:P0A3U8; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR InterPro; IPR007497; DUF541.
DR Pfam; PF04402; SIMPL; 1.
PE 3: Inferred from homology;
KW Periplasm; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000250"
FT CHAIN 29..250
FT /note="26 kDa periplasmic immunogenic protein"
FT /id="PRO_0000020826"
SQ SEQUENCE 250 AA; 26552 MW; 5AF9421FA116F562 CRC64;
MNTRASNFLA ASFSTIMLVG AFSLPAFAQE NQMTTQPARI AVTGEGMMTA SPDMAILNLS
VLRQAKTARE AMTANNEAMT KVLDAMKKAG IEDRDLQTGG INIQPIYVYP DDKNNLKEPT
ITGYSVSTSL TVRVRELANV GKILDESVTL GVNQGGDLNL VNDNPSAVIN EARKRAVANA
IAKAKTLADA AGVGLGRVVE ISELSRPPMP MPIARGQFRT MLAAAPDNSV PIAAGENSYN
VSVNVVFEIK
