ID   T151B_MOUSE             Reviewed;         561 AA.
AC   Q68FE7; Q5XJV8;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Transmembrane protein 151B;
GN   Name=Tmem151b; Synonyms=Gm323;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM151 family. {ECO:0000305}.
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DR   EMBL; BC079879; AAH79879.1; -; mRNA.
DR   EMBL; BC083182; AAH83182.1; -; mRNA.
DR   CCDS; CCDS28810.1; -.
DR   RefSeq; NP_001013771.1; NM_001013749.2.
DR   AlphaFoldDB; Q68FE7; -.
DR   STRING; 10090.ENSMUSP00000136337; -.
DR   iPTMnet; Q68FE7; -.
DR   PhosphoSitePlus; Q68FE7; -.
DR   SwissPalm; Q68FE7; -.
DR   PaxDb; Q68FE7; -.
DR   PRIDE; Q68FE7; -.
DR   ProteomicsDB; 254803; -.
DR   Antibodypedia; 65189; 71 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000180252; ENSMUSP00000136337; ENSMUSG00000096847.
DR   GeneID; 210573; -.
DR   KEGG; mmu:210573; -.
DR   UCSC; uc008cqu.2; mouse.
DR   CTD; 441151; -.
DR   MGI; MGI:2685169; Tmem151b.
DR   VEuPathDB; HostDB:ENSMUSG00000096847; -.
DR   eggNOG; ENOG502QSYQ; Eukaryota.
DR   GeneTree; ENSGT00390000013762; -.
DR   HOGENOM; CLU_023650_2_0_1; -.
DR   InParanoid; Q68FE7; -.
DR   OMA; CRHIPRV; -.
DR   OrthoDB; 542596at2759; -.
DR   PhylomeDB; Q68FE7; -.
DR   TreeFam; TF315223; -.
DR   BioGRID-ORCS; 210573; 1 hit in 73 CRISPR screens.
DR   ChiTaRS; Tmem151b; mouse.
DR   PRO; PR:Q68FE7; -.
DR   Proteomes; UP000000589; Chromosome 17.
DR   RNAct; Q68FE7; protein.
DR   Bgee; ENSMUSG00000096847; Expressed in primary visual cortex and 124 other tissues.
DR   Genevisible; Q68FE7; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026767; Tmem151.
DR   PANTHER; PTHR31893; PTHR31893; 1.
DR   Pfam; PF14857; TMEM151; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..561
FT                   /note="Transmembrane protein 151B"
FT                   /id="PRO_0000307221"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          489..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..505
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   561 AA;  61706 MW;  0F92F03E661ECF1D CRC64;
     MSPPGSAAGE SAGGGGGGGG SGVPEEPMAS ADEGPAREEQ RPIQPSFTKS LCRESHWKCL
     LLSLLMYGCL GAVAWCHVTT VTRLTFSSAY QGNSLMYHDS PCSNGYVYIP LAFLLMLYAV
     YLVECWHCQA RHELQHRVDV SSVQERVGRM QQATPCIWWK AISYHYVRRT RQVTRYRNGD
     AYTTTQVYHE RVNTHVAEAE FDYARCGVRD VSKTLVGLEG APATRLRFTK CFSFASVEAE
     NAYLCQRARF FAENEGLDDY MEAREGMHLK NVDFREFMVA FPDPARPPWY ACSSAFWAAA
     LLTLSWPLRV LAEYRTAYAH YHVEKLFGLE GPGSASSVGG GLSPSDELLP PLTHRLPRVN
     TVDSTELEWH IRSNQQLVPS YSEVLLMDLV ELGSRCGGPG GSYVPRCRYG GVGGPGAAGV
     TPHWRSCEHC QRAVSSSSIF SRSALSICAS PRAAQGPGAS AGCGGSRFSL SRLYGSRRSC
     LWRSRSGSVN EASCPTEQTR LSSQASMRDN EEDEDEEEAG PPPPYQDALC FPVLIVHRQE
     GCLGHSHRSL HRHGSCVETS L