T17B1_CAEEL
ID T17B1_CAEEL Reviewed; 181 AA.
AC O44477;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Probable mitochondrial import inner membrane translocase subunit tim-17B.1 {ECO:0000305};
GN Name=timm-17B.1 {ECO:0000312|WormBase:E04A4.5};
GN Synonyms=tim-17 {ECO:0000312|WormBase:E04A4.5},
GN timm-17 {ECO:0000312|WormBase:E04A4.5};
GN ORFNames=E04A4.5 {ECO:0000312|WormBase:E04A4.5};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Essential component of the TIM23 complex, a complex that
CC mediates the translocation of transit peptide-containing proteins
CC across the mitochondrial inner membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the Tim17/Tim22/Tim23 family. {ECO:0000305}.
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DR EMBL; FO081039; CCD68707.1; -; Genomic_DNA.
DR PIR; T32609; T32609.
DR RefSeq; NP_500627.1; NM_068226.5.
DR AlphaFoldDB; O44477; -.
DR SMR; O44477; -.
DR BioGRID; 42371; 3.
DR STRING; 6239.E04A4.5; -.
DR EPD; O44477; -.
DR PaxDb; O44477; -.
DR PeptideAtlas; O44477; -.
DR EnsemblMetazoa; E04A4.5.1; E04A4.5.1; WBGene00017119.
DR GeneID; 177242; -.
DR KEGG; cel:CELE_E04A4.5; -.
DR UCSC; E04A4.5; c. elegans.
DR CTD; 177242; -.
DR WormBase; E04A4.5; CE16966; WBGene00017119; timm-17B.1.
DR eggNOG; KOG1652; Eukaryota.
DR GeneTree; ENSGT00390000017780; -.
DR HOGENOM; CLU_087811_1_1_1; -.
DR InParanoid; O44477; -.
DR OMA; CPWVILS; -.
DR OrthoDB; 1590221at2759; -.
DR PhylomeDB; O44477; -.
DR PRO; PR:O44477; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00017119; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005744; C:TIM23 mitochondrial import inner membrane translocase complex; IBA:GO_Central.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR InterPro; IPR005678; Tim17.
DR TIGRFAMs; TIGR00980; 3a0801so1tim17; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..181
FT /note="Probable mitochondrial import inner membrane
FT translocase subunit tim-17B.1"
FT /id="PRO_0000210289"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 137..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 181 AA; 19096 MW; 505D8F8CB2BBE9DB CRC64;
MEEYTREPCP YRIGDDIGSA FAMGLVGGSI FQAFGGYKNA AKGKKLVGMM REVRMRSTLT
GVQFAAWGGM FSTIDCCLVA IRKKEDPINS IVSGGLTGAL LAIRSGPKVM AGSAILGSVI
LAMIEGVGLV TTRWMGAMMD PTQPPPEALD DPRSLGQKSQ AEPGLDQTRP FGIPTGLPNL
S
