ID   T1843_DICDI             Reviewed;         351 AA.
AC   Q54WM0;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Transmembrane protein 184 homolog DDB_G0279555;
GN   Name=tmem184C; ORFNames=DDB_G0279555;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Probable transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TMEM184 family. {ECO:0000305}.
CC   -!- CAUTION: Despite its name, this protein may not be the one-to-one
CC       ortholog of TMEM184C. {ECO:0000305}.
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DR   EMBL; AAFI02000031; EAL67716.1; -; Genomic_DNA.
DR   RefSeq; XP_641697.1; XM_636605.1.
DR   AlphaFoldDB; Q54WM0; -.
DR   STRING; 44689.DDB0304957; -.
DR   PaxDb; Q54WM0; -.
DR   EnsemblProtists; EAL67716; EAL67716; DDB_G0279555.
DR   GeneID; 8622106; -.
DR   KEGG; ddi:DDB_G0279555; -.
DR   dictyBase; DDB_G0279555; tmem184C.
DR   eggNOG; KOG2641; Eukaryota.
DR   HOGENOM; CLU_012923_1_3_1; -.
DR   InParanoid; Q54WM0; -.
DR   OMA; YIYITVI; -.
DR   PhylomeDB; Q54WM0; -.
DR   PRO; PR:Q54WM0; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; PTHR23423; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..351
FT                   /note="Transmembrane protein 184 homolog DDB_G0279555"
FT                   /id="PRO_0000379801"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          327..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        26
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        236
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        301
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        304
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   351 AA;  40931 MW;  A159FD9A39D9EFD9 CRC64;
     MWIVAGVCSG VAILLSFYLI YKHLRNYTNP ELQKYIVRIL IMVPIYSVDS WLSLRFVELS
     LYFDVVRDTY EAYVLYCFFS LIVAYIERDF DLVELLHSKE PLPHPFPLTC LPKIKLDRGF
     LTNCKRFVLQ FVFIKPIVAI ISLVLETQHK YGEGKFQVGT GYVWLTVVEN ISVGLSLYFL
     VLYYKAMEEE LKPFKPLGKF LCIKSILFFS FWQSIAISFL VYFGVISPIG SWSVDNISSA
     LQDFITCVEM VILAICHHFF FNYQEFRDPH KVPFIYDKTT KTFFNNPKTN ITPIIKNFFT
     NVTNISDVIS DTRETFILPL LSPDHHHNHP TTKKKDEESN LLEPEDKDII I