ID   T184C_BOVIN             Reviewed;         438 AA.
AC   Q17QL9;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Transmembrane protein 184C;
DE   AltName: Full=Transmembrane protein 34;
GN   Name=TMEM184C; Synonyms=TMEM34;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possible tumor suppressor which may play a role in cell
CC       growth. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM184 family. {ECO:0000305}.
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DR   EMBL; BC118282; AAI18283.1; -; mRNA.
DR   RefSeq; NP_001068648.1; NM_001075180.1.
DR   AlphaFoldDB; Q17QL9; -.
DR   STRING; 9913.ENSBTAP00000013696; -.
DR   PaxDb; Q17QL9; -.
DR   GeneID; 504966; -.
DR   KEGG; bta:504966; -.
DR   CTD; 55751; -.
DR   eggNOG; KOG2641; Eukaryota.
DR   HOGENOM; CLU_012923_1_1_1; -.
DR   InParanoid; Q17QL9; -.
DR   OrthoDB; 462913at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; PTHR23423; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..438
FT                   /note="Transmembrane protein 184C"
FT                   /id="PRO_0000287566"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          358..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..388
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..420
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        423..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  50000 MW;  5DAE67B9505B2F68 CRC64;
     MPCTCTWRNW RQWIRPLAVV LYLLSIVVAV PLCVWELQKL EVGIHTKAWF IAGIFLLLTI
     PISLWVILQH LVHYTQPELQ KPIIRILWMV PIYSLDSWIA LKYPSIAIYV DTCRECYEAY
     VIYNFMGFLT NYLTNRYPNL VLIIEAKDQQ KHFPPLCCCP PWTMGEVLLF RCKLGVLQYT
     VVRPFTTIIA LVCELLDIYD EGNFSFSNAW TYLVIINNMS QLFAMYCLLL FYKVLKEELS
     PIQPVGKFLC VKLVVFVSFW QAVVIALLVK VGVISEKHTW EWQTVEAVAT GLQDFIICIE
     MFLAAIAHHY TFSYKPYVQE AEEGSCFDSF LAMWDVSDIR DDISEQVRHV GRTVMGHPRK
     KFFPEDQDQN EHTSLLSSSS QDALSVASSV PPSPVGHYQG FGHTVTPQTT PTTANASDDT
     GNDAAGVREE PSEKPVAS