ID   T184C_CHICK             Reviewed;         445 AA.
AC   Q5ZMP3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Transmembrane protein 184C;
DE   AltName: Full=Transmembrane protein 34;
GN   Name=TMEM184C; Synonyms=TMEM34; ORFNames=RCJMB04_1i7;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May play a role in cell growth. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM184 family. {ECO:0000305}.
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DR   EMBL; AJ719341; CAG31000.1; -; mRNA.
DR   RefSeq; NP_001008468.1; NM_001008468.1.
DR   AlphaFoldDB; Q5ZMP3; -.
DR   STRING; 9031.ENSGALP00000016253; -.
DR   PaxDb; Q5ZMP3; -.
DR   Ensembl; ENSGALT00000016272; ENSGALP00000016253; ENSGALG00000010019.
DR   GeneID; 422469; -.
DR   KEGG; gga:422469; -.
DR   CTD; 55751; -.
DR   VEuPathDB; HostDB:geneid_422469; -.
DR   eggNOG; KOG2641; Eukaryota.
DR   GeneTree; ENSGT00940000155201; -.
DR   HOGENOM; CLU_012923_1_1_1; -.
DR   InParanoid; Q5ZMP3; -.
DR   OMA; QKWIVAV; -.
DR   OrthoDB; 462913at2759; -.
DR   PhylomeDB; Q5ZMP3; -.
DR   TreeFam; TF324245; -.
DR   PRO; PR:Q5ZMP3; -.
DR   Proteomes; UP000000539; Chromosome 4.
DR   Bgee; ENSGALG00000010019; Expressed in ovary and 14 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; PTHR23423; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..445
FT                   /note="Transmembrane protein 184C"
FT                   /id="PRO_0000287571"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          369..393
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          421..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..393
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        428..445
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   445 AA;  50930 MW;  7279F1078F94FDDD CRC64;
     MPCTCGNWRR WIRPLVVLLY IVGLLVVVPL CVWELQKLEV GIHTKAWFIA GIFLLMTIPI
     SLWGILQHLV HYTQPELQKP IIRILWMVPI YSLDSWIALK YPNIAIYVDT CRECYEAYVI
     YNFMVFLSNY LTNRYPNLVL IIEAKDQQRH LPPLCCCPSW AMGEVLLFRC KLGVLQYTVV
     RPFTTIIALI CELVGVYDEG NFSFDNAWTY LVILNNMSQL FAMYCLVLFY KVLREELNPI
     QPVGKFLCVK MVVFVSFWQA VLIALLVKVG VISEKHTWEW QSVEAVATGL QDFIICVEMF
     LAAIAHHYSF SYKPYVQEAE EGSCFDSFLA MWDISDIRAD ISEQVRNVGR TVLGQPRKMF
     FAEDHEQNEH TSLLSSSTQD PISDASSMPS SPMGHYQGFG HTVTPLTTPT TVPVVDGIYN
     TSATRDTEES PELMHNSSEK ALDRS