ID   T184C_RAT               Reviewed;         503 AA.
AC   Q810F5;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Transmembrane protein 184C;
DE   AltName: Full=Transmembrane protein 34;
GN   Name=Tmem184c; Synonyms=Tmem34;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Wistar; TISSUE=Bone marrow;
RA   Buki K.G., Vaananen K.;
RT   "Novel genes in rat bone marrow.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Possible tumor suppressor which may play a role in cell
CC       growth. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM184 family. {ECO:0000305}.
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DR   EMBL; AY228474; AAO73557.1; -; mRNA.
DR   EMBL; BC089112; AAH89112.1; -; mRNA.
DR   RefSeq; NP_847900.1; NM_178330.1.
DR   AlphaFoldDB; Q810F5; -.
DR   STRING; 10116.ENSRNOP00000017225; -.
DR   PaxDb; Q810F5; -.
DR   GeneID; 291946; -.
DR   KEGG; rno:291946; -.
DR   UCSC; RGD:727852; rat.
DR   CTD; 55751; -.
DR   RGD; 727852; Tmem184c.
DR   VEuPathDB; HostDB:ENSRNOG00000012860; -.
DR   eggNOG; KOG2641; Eukaryota.
DR   HOGENOM; CLU_012923_1_1_1; -.
DR   InParanoid; Q810F5; -.
DR   OMA; QKWIVAV; -.
DR   OrthoDB; 462913at2759; -.
DR   PhylomeDB; Q810F5; -.
DR   TreeFam; TF324245; -.
DR   PRO; PR:Q810F5; -.
DR   Proteomes; UP000002494; Chromosome 19.
DR   Bgee; ENSRNOG00000012860; Expressed in ovary and 19 other tissues.
DR   Genevisible; Q810F5; RN.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; PTHR23423; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..503
FT                   /note="Transmembrane protein 184C"
FT                   /id="PRO_0000287570"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          358..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          479..503
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..391
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   503 AA;  57917 MW;  60D93297353A30D7 CRC64;
     MPCACNRNNW RKWIRPLLIL LYALAILVTV PVCIWEFQKL KVGIHTKVWF IAGIFLLLTI
     PVSMCGILQH LVHYTQPELQ KPIIRILWMV PIYSLDSWVA LKYPKIAIYV DTWRECYEAY
     VIYNFMIFLT NYLTIRFPNL MLHLEAKDQQ NHLPPLCCCP PWAMGEMLLF RCKLGVLQYT
     VVRPITTVTS LVCEILGVYD EGNFSFSNAW TYLVILNNLS QLFAMYCLLL FYKVLKEELS
     PIQPVGKFLC VKLVVFVSFW QAVLIALLVK VGVISEKRTW EWQSAEAVAT GLQDFIICIE
     MFFAAIAHHY TFSYKPYVHE AEEGPCFDSF LAMWDVSDIR EDISEQVRRV GRTMRGYPKK
     KCFPGDPDHN EHSSLLSASS QDSSKPSSPV GLYQGFGQTI TSQSPISIAN LYEEILNEIP
     EEQQRLYSGQ DITMDIPEEQ PRHDTGQDVV HLPYRQELPY KNHYQDHIQT VTSRYLLSSP
     KPSDDIVIDF SDSPEGSDSS TDS