ID   T184C_XENTR             Reviewed;         443 AA.
AC   Q28CV2;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Transmembrane protein 184C;
DE   AltName: Full=Transmembrane protein 34;
GN   Name=tmem184c; Synonyms=tmem34;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in cell growth. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TMEM184 family. {ECO:0000305}.
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DR   EMBL; CR926175; CAJ83307.1; -; mRNA.
DR   RefSeq; NP_001016532.1; NM_001016532.2.
DR   AlphaFoldDB; Q28CV2; -.
DR   SMR; Q28CV2; -.
DR   STRING; 8364.ENSXETP00000015464; -.
DR   PaxDb; Q28CV2; -.
DR   GeneID; 549286; -.
DR   KEGG; xtr:549286; -.
DR   CTD; 55751; -.
DR   Xenbase; XB-GENE-1016397; tmem184c.
DR   eggNOG; KOG2641; Eukaryota.
DR   HOGENOM; CLU_012923_1_1_1; -.
DR   InParanoid; Q28CV2; -.
DR   OMA; YAVNAWL; -.
DR   OrthoDB; 462913at2759; -.
DR   PhylomeDB; Q28CV2; -.
DR   TreeFam; TF324245; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   ExpressionAtlas; Q28CV2; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   InterPro; IPR005178; Ostalpha/TMEM184C.
DR   PANTHER; PTHR23423; PTHR23423; 1.
DR   Pfam; PF03619; Solute_trans_a; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..443
FT                   /note="Transmembrane protein 184C"
FT                   /id="PRO_0000287573"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          369..422
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..415
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   443 AA;  50261 MW;  69B95D4829A24E42 CRC64;
     MPCTCGNWRR WIRPLVVLLY IVGLIVGVPI CIWKLQKMEV GVHTKAWFIA GIFVLMTIPI
     SLWGILQHLV HYTQPELQKP IIRILWMVPI YSVDSWIALK YPDIAIYVDT CRECYEAYVI
     YNFMIFLLNY LTNRCPNLAL VLEAKDQQRH LPPLCCCPPW AMGDVLLFRC KLGVLQYTVV
     RPVTTVIALI CQLTGVYGEG DFSVKNAWTY LVIINNVSQV FAMYCLVLFY KVLKEELNPI
     QPVGKFLCVK MVVFVSFWQA VFIAILVKAG VISNTWEWKK VQDVATGLQD FIICVEMFLA
     AVAHHFSFTY KPYVQEAEEG SCFDSFLAMW DISDIRADIS EQVRNVGRTV LGRPRKMFFN
     DDLEQNEHTS LLSSSTQDPI SAASSIPPSP SGHYQGFGQT ITPQTTPTAT TMPEELYSAD
     SPEADLVADH SKVPDESCNH LDS