ID   T185L_DICDI             Reviewed;         490 AA.
AC   Q7KWT1; Q551W9;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Transmembrane protein 185-like;
GN   ORFNames=DDB_G0276293;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the TMEM185 family. {ECO:0000305}.
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DR   EMBL; AAFI02000014; EAL69293.1; -; Genomic_DNA.
DR   RefSeq; XP_643209.1; XM_638117.1.
DR   AlphaFoldDB; Q7KWT1; -.
DR   STRING; 44689.DDB0232081; -.
DR   PaxDb; Q7KWT1; -.
DR   EnsemblProtists; EAL69293; EAL69293; DDB_G0276293.
DR   GeneID; 8620412; -.
DR   KEGG; ddi:DDB_G0276293; -.
DR   dictyBase; DDB_G0276293; -.
DR   eggNOG; KOG3879; Eukaryota.
DR   HOGENOM; CLU_557156_0_0_1; -.
DR   InParanoid; Q7KWT1; -.
DR   OMA; WRIVGSI; -.
DR   PRO; PR:Q7KWT1; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   InterPro; IPR019396; TM_Fragile-X-F-assoc.
DR   PANTHER; PTHR13568; PTHR13568; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..490
FT                   /note="Transmembrane protein 185-like"
FT                   /id="PRO_0000389206"
FT   REGION          1..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          455..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        463..477
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   490 AA;  53899 MW;  6F2E331E48EC9ADD CRC64;
     MIENENTSLL STSSSSTSSS PNNANSPSSL NIGISNSENG TPRKDNTSGN NSPSAQITKY
     NGIDISNNSS RNSSRPNSRS GYRGDSSSNN NNNNNNNNNN NNNNNNINKH NSIVYNKSNN
     KLNSIGGSNN DLQGGGGGNG NGNGNGSSKY KIGINNKDVE EKIEIKKQKK MNRTNNQKFW
     RIVGSILQII GLSSIVFTIF IGLYIDGYID WSYWILFIPV YVILAASYLA TGSRVLSNLV
     SWIIRLVWRL SVFGLTVFVV FTIIHFKYNT FGFSVMMIPL LFTFGSVFVM GIFSLLFGII
     FVDGKSTPQR KTKYIVNGLP LLFTGAILTP AAIMIALKLD GLYDAKLAVC FVSLFIGDII
     ASCFSFFLLI FSLGSKDTAT FSIGQLLSII FITICSIVFK VLLILATDQQ HNINSLFLLI
     PLLVAEAFMV FCGINLFLRP PRVIVDNSEE LAKSNMINNQ DSSESESDDE TEVSFKDRED
     EESEKLISNL